Title:
SIX-MEMBERED-HETEROCYCLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2016/204134
Kind Code:
A1
Abstract:
The present invention relates to a compound, or a pharmacologically acceptable salt thereof, that is represented by general formula (I) and that has excellent hypoglycemic action. [In the formula, double lines that include a broken line indicate a single bond or a double bond, R1 is a hydrogen atom, a C1-3 alkyl group, or the like, R2 is a hydrogen atom, a C1-3 alkyl group, or the like, R3 is a hydrogen atom, a C1-6 alkyl group, or the like, R4 is a hydrogen atom, a C1-6 alkyl group, or the like, R5 is a hydrogen atom or the like, R6 is a C2-6 alkyl group or the like, R7 is a hydrogen atom or the like, V is -CH2- or -C(=O)-, W is a phenyl group or the like that may be substituted with 1-4 identical or different substituents selected from substituent group α, substituent group α comprises C1-3 alkyl groups or the like, X is -CH=, -CH2-, -O-, or -N=, Y is -CR3R4-, -NR5- or -CR6=, and Z is -CH2-, -O-, or -NR7-, provided that when V is -C(=O)- and X and Z are -CH2-, Y is not -CR3R4-.]
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Inventors:
SHINOZUKA TSUYOSHI (JP)
NAMIKI HIDENORI (JP)
OCHIAI YUICHI (JP)
MATSUSHITA KAORU (JP)
NISHI TATSUYA (JP)
YAMANOI SHIGEO (JP)
NAMIKI HIDENORI (JP)
OCHIAI YUICHI (JP)
MATSUSHITA KAORU (JP)
NISHI TATSUYA (JP)
YAMANOI SHIGEO (JP)
Application Number:
PCT/JP2016/067616
Publication Date:
December 22, 2016
Filing Date:
June 14, 2016
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C07D491/052; A61K31/436; A61K31/4433; A61K31/444; A61K31/501; A61K31/519; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; C07D491/107; C07D493/04
Domestic Patent References:
| WO2014061764A1 | 2014-04-24 | |||
| WO2014142127A1 | 2014-09-18 |
Foreign References:
| JP2001039984A | 2001-02-13 | |||
| US20130324525A1 | 2013-12-05 |
Other References:
KEUPER,R. ET AL.: "Synthesis and characterization of novel pyridines and 3,3'-bridged bipyridines using 1, x-cyclohexanediones", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 11, 1998, pages 2609 - 2615, XP055337630
YOU,X. ET AL.: "Synthesis of 9-aryl-3-methyl-1, 8-dioxo-2,10-dioxanthens", CHIN. J. ORG. CHEM., vol. 32, no. 1, 2012, pages 156 - 159
YOU,X. ET AL.: "Synthesis of 9-aryl-3-methyl-1, 8-dioxo-2,10-dioxanthens", CHIN. J. ORG. CHEM., vol. 32, no. 1, 2012, pages 156 - 159
Attorney, Agent or Firm:
ISHIBASHI, Koki et al. (JP)
Kimiki Ishibashi (JP)
Kimiki Ishibashi (JP)
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