Title:
SOLID PHARMACEUTICAL TABLET, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2014/007065
Kind Code:
A1
Abstract:
Disclosed are a solid pharmaceutical tablet and a method for producing the solid pharmaceutical tablet. The solid pharmaceutical tablet according to the present invention comprises atorvastatin or a salt or hydrate thereof and amlodipine or a pharmaceutically acceptable salt thereof, and is produced by film-coating a mixture of atorvastatin or a salt or hydrate thereof and amlodipine or a pharmaceutically acceptable salt thereof with a coating agent comprising polyvinyl alcohol and/or a vinyl alcohol copolymer. In the solid pharmaceutical tablet according to the present invention, the production of analogous substances of the active ingredients is inhibited. Therefore, the solid pharmaceutical tablet has excellent stability.
Inventors:
JO TAKAAKI (JP)
HACHIYANAGI HIDEO (JP)
KATAYAMA NAOHISA (JP)
HACHIYANAGI HIDEO (JP)
KATAYAMA NAOHISA (JP)
Application Number:
PCT/JP2013/066874
Publication Date:
January 09, 2014
Filing Date:
June 19, 2013
Export Citation:
Assignee:
NIPRO CORP (JP)
International Classes:
A61K31/40; A61K9/30; A61K31/402; A61K31/4422; A61K47/02; A61K47/20; A61K47/32; A61P3/06; A61P9/12
Domestic Patent References:
| WO2011077843A1 | 2011-06-30 | |||
| WO2006070248A1 | 2006-07-06 |
Foreign References:
| JP2008519835A | 2008-06-12 | |||
| JP2012001460A | 2012-01-05 | |||
| JP2006306754A | 2006-11-09 |
Other References:
TOSHIO HAGIWARA ET AL.: "Amlodipine Besylate/Atorvastatin Calcium Suiwabutsu Haigojo (Caduet Haigojo 1 Ban/2 Ban/3 Ban/ 4 Ban)", DRUG INFORMATION, vol. 16, no. 12, December 2009 (2009-12-01), pages 1112 - 1115
Attorney, Agent or Firm:
SHINDO, Takuya et al. (JP)
Takuya Shindo (JP)
Takuya Shindo (JP)
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