Title:
SPIROFORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACEUTICALS
Document Type and Number:
WIPO Patent Application WO/2018/214862
Kind Code:
A1
Abstract:
A spiroformamide derivative, a preparation method therefor, and an application thereof for use in pharmaceuticals. In particular, a spiroformamide derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutical composition containing the derivative, a use thereof as an ROR modulator, and a use thereof for the prevention and/or treatment of diseases such as inflammation, autoimmune diseases, and cancers, substituents in general formula (AI) being the same as those defined in the description.
Inventors:
QIAN WENJIAN (CN)
LI XIN (CN)
JIANG HONGJIAN (CN)
LIU DONG (CN)
LIU SUXING (CN)
ZHANG RUMIN (CN)
HE FENG (CN)
TAO WEIKANG (CN)
LI XIN (CN)
JIANG HONGJIAN (CN)
LIU DONG (CN)
LIU SUXING (CN)
ZHANG RUMIN (CN)
HE FENG (CN)
TAO WEIKANG (CN)
Application Number:
PCT/CN2018/087781
Publication Date:
November 29, 2018
Filing Date:
May 22, 2018
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/14; A61K31/437; A61P35/00; A61P37/00
Domestic Patent References:
| WO2015083130A1 | 2015-06-11 | |||
| WO2016064970A1 | 2016-04-28 |
Foreign References:
| CN105940002A | 2016-09-14 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
Download PDF: