Title:
STEVIOL GLYCOSYLTRANSFERASE AND GENE ENCODING SAME
Document Type and Number:
WIPO Patent Application WO/2013/180306
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a steviol glycosyltransferase; and a method for producing a steviol glycoside using the glycosyltransferase.
The present invention provides: a steviol glycosyltransferase; and a method for producing a steviol glycoside using the glycosyltransferase. The present invention also provides: a transformant having a steviol glycosyltransferase gene introduced therein; and a method for producing the transformant.
Inventors:
ONO EIICHIRO (JP)
Application Number:
PCT/JP2013/065518
Publication Date:
December 05, 2013
Filing Date:
May 29, 2013
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
C12N15/09; A01H5/00; A23L27/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12P19/18
Domestic Patent References:
| WO2012075030A1 | 2012-06-07 |
Foreign References:
| JPS5430199A | 1979-03-06 | |||
| EP1897951B1 | 2010-12-15 | |||
| JPH05255372A | 1993-10-05 | |||
| JP2005287403A | 2005-10-20 | |||
| US6045996A | 2000-04-04 | |||
| US5925525A | 1999-07-20 | |||
| US5858659A | 1999-01-12 |
Other References:
RICHMAN A. ET AL.: "Functional genomics uncovers three glucosyltransferases involved in the synthesis of the major sweet glucosides of Stevia rebaudiana.", PLANT J., vol. 41, no. 1, 2005, pages 56 - 67, XP002686584
SHIBATA H. ET AL.: "Steviol and steviol-glycoside: glucosyltransferase activities in Stevia rebaudiana Bertoni--purification and partial characterization.", ARCH.BIOCHEM. BIOPHYS., vol. 321, no. 2, 20 August 1995 (1995-08-20), pages 390 - 396, XP055172978
EIICHIRO ONO ET AL.: "Diterpene Kanmiryo Rebaudioside A no Seigosei ni Kakawaru Stevia Shinki Haitotaika Koso no Dotei", DAI 54 KAI PROCEEDINGS OF THE ANNUAL MEETING OF THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS, 14 March 2013 (2013-03-14), pages 230, 3AH10, XP008175664
See also references of EP 2862927A4
BRANDLE; TELMER, PHYTOCHEMISTRY, vol. 68, 2007, pages 1855 - 1863
RICHMAN ET AL., PLANT J., vol. 41, 2005, pages 56 - 67
MIZUTANI; OHTA, ANNU. REV. PLANT BIOL., vol. 61, 2010, pages 291 - 315
KASAI ET AL., JOURNAL OF THE CHEMICAL SOCIETY OF JAPAN, vol. 5, 1981, pages 726 - 735
SAMBROOK; RUSSELL: "Molecular Cloning: A Laboratory Manual", vol. 3, 2001, COLD SPRING HARBOR LABORATORY PRESS
AUSUBEL: "Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
NUC. ACIDS. RES., vol. 10, 1982, pages 6487
PROC. NATL. ACAD. SCI. USA, vol. 79, 1982, pages 6409
GENE, vol. 34, 1985, pages 315
NUC. ACIDS. RES., vol. 13, 1985, pages 4431
PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 488
SCIENCE, vol. 227, no. 4693, 1985, pages 1435 - 1441
PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 2264 - 2268
PROC NATL ACAD SCI USA, vol. 90, 1993, pages 5873
ALTSCHUL SF ET AL., J MOL BIOL, vol. 215, 1990, pages 403
MARIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 81, 1984, pages 337
JUNJI INOKOSHI ET AL., BIOCHEMISTRY, vol. 64, 1992, pages 660
HUSSAIN ET AL., GENE, vol. 101, 1991, pages 149
MACKENXIE, D. A. ET AL., APPL. ENVIRON. MICROBIOL., vol. 66, 2000, pages 4655 - 4661
PROC. NATL. ACAD. SCI. USA, vol. 75, 1978, pages 1929
J. BACTERIOLOGY, vol. 153, 1983, pages 163
"Methods in yeast genetics", 2000, COLD SPRING HARBOR LABORATORY COURSE MANUAL
"Methods in Yeast Genetics, A laboratory manual", COLD SPRING HARBOR LABORATORY PRESS
HIROFUMI MIYAUCHI: "Manuals for Plant Genetic Engineering", 1990, KODANSHA SCIENTIFIC LTD., pages: 27 - 31
NAGEL ET AL., MICRIBIOL. LETT., vol. 67, 1990, pages 325
GELVIN, S.B. ET AL.: "Plant Molecular Biology Manual", ACADEMIC PRESS PUBLISHERS
SAMBROOK; FRITSCH; MANIATIS: "Molecular Cloning: A Laboratory Manual 2nd Edition", 1989, COLD SPRING HARBOR LABORATORY PRESS
SIEBEN V. J. ET AL., IET NANOBIOTECHNOLOGY, vol. 1, no. 3, June 2007 (2007-06-01), pages 27 - 35
SHIBATA H. ET AL.: "Steviol and steviol-glycoside: glucosyltransferase activities in Stevia rebaudiana Bertoni--purification and partial characterization.", ARCH.BIOCHEM. BIOPHYS., vol. 321, no. 2, 20 August 1995 (1995-08-20), pages 390 - 396, XP055172978
EIICHIRO ONO ET AL.: "Diterpene Kanmiryo Rebaudioside A no Seigosei ni Kakawaru Stevia Shinki Haitotaika Koso no Dotei", DAI 54 KAI PROCEEDINGS OF THE ANNUAL MEETING OF THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS, 14 March 2013 (2013-03-14), pages 230, 3AH10, XP008175664
See also references of EP 2862927A4
BRANDLE; TELMER, PHYTOCHEMISTRY, vol. 68, 2007, pages 1855 - 1863
RICHMAN ET AL., PLANT J., vol. 41, 2005, pages 56 - 67
MIZUTANI; OHTA, ANNU. REV. PLANT BIOL., vol. 61, 2010, pages 291 - 315
KASAI ET AL., JOURNAL OF THE CHEMICAL SOCIETY OF JAPAN, vol. 5, 1981, pages 726 - 735
SAMBROOK; RUSSELL: "Molecular Cloning: A Laboratory Manual", vol. 3, 2001, COLD SPRING HARBOR LABORATORY PRESS
AUSUBEL: "Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
NUC. ACIDS. RES., vol. 10, 1982, pages 6487
PROC. NATL. ACAD. SCI. USA, vol. 79, 1982, pages 6409
GENE, vol. 34, 1985, pages 315
NUC. ACIDS. RES., vol. 13, 1985, pages 4431
PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 488
SCIENCE, vol. 227, no. 4693, 1985, pages 1435 - 1441
PROC. NATL. ACAD. SCI. USA, vol. 87, 1990, pages 2264 - 2268
PROC NATL ACAD SCI USA, vol. 90, 1993, pages 5873
ALTSCHUL SF ET AL., J MOL BIOL, vol. 215, 1990, pages 403
MARIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 81, 1984, pages 337
JUNJI INOKOSHI ET AL., BIOCHEMISTRY, vol. 64, 1992, pages 660
HUSSAIN ET AL., GENE, vol. 101, 1991, pages 149
MACKENXIE, D. A. ET AL., APPL. ENVIRON. MICROBIOL., vol. 66, 2000, pages 4655 - 4661
PROC. NATL. ACAD. SCI. USA, vol. 75, 1978, pages 1929
J. BACTERIOLOGY, vol. 153, 1983, pages 163
"Methods in yeast genetics", 2000, COLD SPRING HARBOR LABORATORY COURSE MANUAL
"Methods in Yeast Genetics, A laboratory manual", COLD SPRING HARBOR LABORATORY PRESS
HIROFUMI MIYAUCHI: "Manuals for Plant Genetic Engineering", 1990, KODANSHA SCIENTIFIC LTD., pages: 27 - 31
NAGEL ET AL., MICRIBIOL. LETT., vol. 67, 1990, pages 325
GELVIN, S.B. ET AL.: "Plant Molecular Biology Manual", ACADEMIC PRESS PUBLISHERS
SAMBROOK; FRITSCH; MANIATIS: "Molecular Cloning: A Laboratory Manual 2nd Edition", 1989, COLD SPRING HARBOR LABORATORY PRESS
SIEBEN V. J. ET AL., IET NANOBIOTECHNOLOGY, vol. 1, no. 3, June 2007 (2007-06-01), pages 27 - 35
Attorney, Agent or Firm:
KOBAYASHI, Hiroshi et al. (JP)
Hiroshi Kobayashi (JP)
Hiroshi Kobayashi (JP)
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