Title:
SUBSTITUTED BIS(PYRIDIN-2-YL)AMINE DERIVATIVE, COMPOSITION THEREOF AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/078309
Kind Code:
A1
Abstract:
Provided are a substituted bis(pyridin-2-yl)amine derivative represented by formula (I), a pharmaceutically acceptable salt, solvate, stereoisomer, prodrug and pharmaceutical composition thereof, and a medical application thereof. The derivative has significant CDK9 selective inhibitory activity and is of great practical value.
More Like This:
| JP6931646 | Benlactam compound |
| JP2005519034 | Pyrimidine compound |
| WO/2018/035359 | THERAPEUTIC COMPOUNDS USEFUL FOR THE PROPHYLACTIC OR THERAPEUTIC TREATMENT OF AN HIV VIRUS INFECTION |
Inventors:
ZHAO ZHIMING (CN)
WU SHENGHUA (CN)
LIU YANG (CN)
HUA MOJIA (CN)
HAO SHENGLEI (CN)
WU SHENGHUA (CN)
LIU YANG (CN)
HUA MOJIA (CN)
HAO SHENGLEI (CN)
Application Number:
PCT/CN2021/123189
Publication Date:
April 21, 2022
Filing Date:
October 12, 2021
Export Citation:
Assignee:
SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN)
YANGTZE RIVER PHARM GROUP CO (CN)
YANGTZE RIVER PHARM GROUP CO (CN)
International Classes:
C07D401/14; A61K31/435; A61K31/537; A61K31/538; A61K31/541; A61K31/554; A61P35/00; C07D401/12; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D498/04
Domestic Patent References:
| WO2019161224A1 | 2019-08-22 |
Foreign References:
| CN105102444A | 2015-11-25 | |||
| CN104854091A | 2015-08-19 | |||
| CN105492438A | 2016-04-13 | |||
| CN106232596A | 2016-12-14 | |||
| CN105324380A | 2016-02-10 |
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
Download PDF: