SUBSTITUTED PYRIMIDINEDIONE AND PHARMACEUTICAL COMPOSITION THEREOF

Title:

SUBSTITUTED PYRIMIDINEDIONE AND PHARMACEUTICAL COMPOSITION THEREOF

Document Type and Number:

WIPO Patent Application WO/2017/181924

Kind Code:

A1

Abstract:

The present invention discloses a substituted pyrimidinedione and a pharmaceutical composition thereof. The substituted pyrimidinedione is a compound represented by formula (I), or a crystalline form, pharmaceutically acceptable salt, prodrug, tautomer, stereoisomer, isotopic isomer, hydrate, or solvate thereof. The compound disclosed by the invention has improved inhibition against a dipeptidyl peptidase, improved pharmacodynamics/pharmacokinetics, good compound usability, and high levels of safety. The compound can be used to prepare a drug for treating a disease related to the dipeptidyl peptidase.

More Like This:

JP2012525336	Pilidinone antagonist of α-4 integrin
JP5619761	2-[(1-Cyanopropyl) carbamoyl] -5-chloromethylnicotinic acid and its use in the manufacture of imidazolinone herbicides
JPS62138476	5-FLUOROACYLAMINO-4-NITRO-1-ARYL-PYRAZOLES

Inventors:

WANG YIHAN (CN)
ZHAO JIUYANG (CN)

Application Number:

PCT/CN2017/080762

Publication Date:

October 26, 2017

Filing Date:

April 17, 2017

Export Citation:

Click for automatic bibliography generation Help

Assignee:

SHENZHEN TARGETRX INC (CN)

International Classes:

C07D401/04; A61K31/513; A61P3/10

Foreign References:

CN1926128A	2007-03-07
CN105272963A	2016-01-27
CN102127057A	2011-07-20

Download PDF:

View/Download PDF PDF Help

Previous Patent: FACIAL VERIFICATION METHOD, DEVICE, AND COMPUTER STORAGE MEDIUM

Next Patent: DISPLAY SUBSTRATE, DISPLAY PANEL, DISPLAY APPARATUS, AND MANUFACTURING METHOD OF DISPLAY SUBSTRATE