SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF

Title:

SULFONIC ESTER DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/1998/005634

Kind Code:

A1

Abstract:

Novel, useful and optically active 2-aralkyl-3-sulfonyloxy-1-propanols and 2-aralkyl-3-sulfonyloxypropionic acids prepared from optically active 2-aralkyl-3-acyloxy-1-propanols as the starting compound; and optically active 2-aralkyl-3-thiopropionic acids as an important intermediate for enkephalinase inhibitors. They are commercially advantageous, optically active sulfonic esters.

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Inventors:

YASOHARA YOSHIHIKO (JP)
MIYAMOTO KENJI (JP)
KAWANO SHIGERU (JP)
HASEGAWA JUNZO (JP)

Application Number:

PCT/JP1997/002699

Publication Date:

February 12, 1998

Filing Date:

August 01, 1997

Export Citation:

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Assignee:

KANEKA CORP (JP)
YASOHARA YOSHIHIKO (JP)
MIYAMOTO KENJI (JP)
KAWANO SHIGERU (JP)
HASEGAWA JUNZO (JP)

International Classes:

C07C303/30; C07C309/64; C07C309/66; C07C309/73; C07C327/32; C07D317/24; (IPC1-7): C07C309/64; C07B53/00; C07C303/30; C07C309/72

Foreign References:

JPS62502259A	1987-09-03
JPH0859606A	1996-03-05

Other References:

TETRAHEDRON LETTERS, 1980, Vol. 21, No. 52, M.B. GROEN et al., "Synthesis of Compound X, a Non-Steroidal Constituent of Female Urine and Congeners", p. 5043-5046.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, August 1994, Vol. 116, No. 17, Y. TANAKA et al., "Conscripting the Active-Site Zinc Ion in Carboxypeptidase A in Inactivation Chemistry by a New Type of Irreversible Enzyme Inactivator", p. 7475-7480.
See also references of EP 0916654A4

Attorney, Agent or Firm:

Itami, Kenji (2-4 Nishitenma 3-chome, Kita-k, Osaka-shi Osaka 530, JP)

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