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Title:
SWEET PRODUCTS WITH FLAVIN CONTENT AND METHODS OF PRODUCING THEREOF
Document Type and Number:
WIPO Patent Application WO/2004/010790
Kind Code:
A1
Abstract:
The invention relates to methods for making sweets products suitable for ensuring flaving requirements of living organisms and products, preferably sweetmeat, drops, chocolate containing flaving suitable for ensurnig flaving requirements of the living organism and for use of sportsmen, diabetics, passengers and people intending to follow a healthy way of life.

Inventors:
HORVATH ISTVAN (HU)
Application Number:
PCT/HU2002/000169
Publication Date:
February 05, 2004
Filing Date:
December 28, 2002
Export Citation:
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Assignee:
HORVATH ISTVAN (HU)
International Classes:
A23G1/00; A23G1/30; A23G1/42; A23G1/48; A23G3/00; A23G3/36; A23G3/48; A23L1/30; (IPC1-7): A23G3/00; A23L1/30
Domestic Patent References:
WO2000001245A22000-01-13
WO1997025876A11997-07-24
WO1998014173A11998-04-09
Foreign References:
FR2739757A31997-04-18
EP0788746A11997-08-13
EP1133924A12001-09-19
US5888563A1999-03-30
US5578336A1996-11-26
US2634210A1953-04-07
GB560631A1944-04-13
GB702015A1954-01-06
Other References:
DATABASE WPI Section Ch Week 199835, Derwent World Patents Index; Class D13, AN 1998-411795, XP002237507
DATABASE WPI Section Ch Week 199207, Derwent World Patents Index; Class B04, AN 1992-053581, XP002237508
PATENT ABSTRACTS OF JAPAN vol. 009, no. 108 (C - 280) 11 May 1985 (1985-05-11)
PATENT ABSTRACTS OF JAPAN vol. 015, no. 100 (C - 0813) 11 March 1991 (1991-03-11)
Attorney, Agent or Firm:
Varga, Tamás Péter (Budapest, HU)
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Claims:
CLAIMS
1. Method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials, then a jelly is made with using proper additives and this jelly is used to produce sweet products.
2. Method according to claim 1 characterized by that, additive used for jellification is saccharides and/or polysaccharide and/or polypeptide.
3. Method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials and together with a solid or soft carrier are put into sweet products used as usual.
4. Method according to claim 3 characterized by that, a carrier is ground grains, and/or meal made from false fruit e. g. applemeal and flavin or flavin derivative is mixed to said carrier.
5. Method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin used as raw materials are lyophilized and powder obtained this way is filled to sweet products in the usual way.
6. Method according to claim 5 characterized by that, lyophilized flavin or flavin derivatives are mixed with solid or soft carriers or additives in given case with ground grains and/or meals made from false fruit e. g. applemeal, or said lyophilized flavin or flavin derivatives are directly added to said sweet products.
7. Method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials, concentration of said raw materials is set and liquid obtained this way is added to sweet products in the usual way.
8. Method according to claim 7 characterized by that, liquid containing flavin of set concentration is mixed to a solid or soft carrier or additive to be used for making sweet products.
9. Sweet product, preferably a sweetmeat of flavin content characterized by that, filling of said sweet product similar in appearance to sweetmeat marketed generally is a vegetal extract or flavin derivative synthesized by bacteria of high flavin content in liquid or jellied form.
10. Product according to claim 9 characterized by that, filling of said product is a fibrous organic material not causing chemical reaction with flavin, can not be digested, or can be digested with difficulty by the body.
11. Product according to any of claims 9 or 10 characterized by that, there is another additive as well in said filling besides filling containing flavin, in given case fruit, for example sour cherry and/or raisin.
12. Sweet product, preferably drops filled with flavin characterized by that said product similar to sweet products contains liquid or jellied flavin derivatives in different concentration and dosage (quantity).
13. Sweet product, preferably chocolate filled with flavin characterized by that, said product similar to filled chocolates is a product filled with flavin jellied or mixed with carriers.
14. Sweet product according to claim 13 characterized by that, said product is made in bars and/or bars divided into pieces and filling of said product contains flavin and is a flavored jelly and/or a fluid containing flavin derivatives mixed to another filling material or said filling is a dry flavin product made by lyofilization or by other drying methods used as usual.
15. Sweet product according to any of claims 9 to 14 characterized by that, said product preferably contains carriers, additives, gelatinizing material used mainly in food industry.
16. Sweet product according to any of claims 9 to 15 characterized by that, said product contains filling materials suitable for use in food industry in given case honey, furthermore carriers suitable for the intake of flavin, in given case applemeal, ground nuts, almond, ground grains and carrier material contains in given case alcohol and flavoring materials.
17. Sweet product according to any of claims 9 to 16 characterized by that, flavin closed in a visible structure is dry or solved in a solvent or closed in a nanocapsule.
18. Sweet product according to any of claims 9 to 17 characterized by that, in case of fluids containing flavin, flavin derivatives are present in said fluid in a soluble state or linked with a carrier cell, or cell scrap in a suspended state.
19. Sweet product according to any of claims 9 to 18 characterized by that, said product is produced in a diabetic version for diabetics and elderly people being in more endangered status.
20. Sweet product according to any of claims 9 to 19 characterized by that, said product contains flavin or flavin derivatives in dosed form.
Description:
Sweet products with flavin content and methods of producing thereof The invention relates to methods for making sweet products suitable for ensuring flavin requirements of living organisms and products, preferably sweetmeat, drops, chocolate containing flavin suitable for ensuring flavin requirements of the living organism and for use of sportsmen, diabetics, passengers and people intending to follow a healthy way of life.

With the help of the methods flavin derivatives (hereinafter referred to as flavin) in dosed form can be placed at consumers'disposal in such a way, that besides being conducive to health and essential supplements to food they result in pleasant effects as candy and confectionery.

Flavin is indispensable for human and animal organisms first of all for synthesis and functioning of mitochondria of cells. Flavoproteins are structure proteins and enzymes at the same time synthesizing mitochondria. They play an important role in the synthesis of metalo-flavoproteins and nucleotides as well. As human and animal organisms are unable of their synthesis, they can rely on flavin derivatives synthesized by plants or eventually by bacteria. In lack of flavin disorders of metabolism arise.

Unfavorable change of permeability and flexibility of veins is the most striking phenomena. Disorders of cardiovascular system, energy system of the organism result from this, but any change of biological processes of cells can be due to this.

So it is obvious, that the organism suffers from lack of flavin derivatives any time, but particularly during increased loading, respectively enjoys abundance of flavin supply.

It is therefore important to cater for flavin supply of air-passengers under increased stress and physical stress, and of sportsmen enabling them to make use of their maximum capacity.

Flavin derivatives are consequently not medicines, they are simply parts of healthy nutrients. In case of its deficiency nutrients of high flavin content, food supplements can be healing or even life-saving.

Historical review: Flavin was discovered in the 19th century. First it was found in milk as'lacto flavin'.

Since then thousands of flavin derivatives have been found. It is true for all flavin derivatives that only bacteria and vegetal organism can synthesize them. This statement should be faced to the fact, that animal and human organisms are not able to function without flavin derivatives. Their affect on arteries first of all on veins has been known for long. (Ambroseand De Eds: J. Pharm. Exper. Ther. 1947. ) Their affect on decreasing blood pressure in connection with the dilatation of arteries has been known from animal tests for long. The physiological affect is due to its strong reducing capacity and synthesizing capacity of flavoprotein and nucleotide. Its role in cholesterol and sterane structure metabolism was noticed long ago. (Levitan: N. Engl.

J Med. 1949). There is no doubt about the essential role of flavin derivatives.

Their deficiency in the organism can result in a wide range of symptoms regarding the circulatory system, influencing metabolism of sterane structure chemicals or in cases of diseases in connection with nucleotide function and regarding disorders in connection with energy production of mitochondria. Recovering the deficiency can obviously result in the same wide range of favorable affects in therapy and preventive medicine.

Hungarian reference: At the beginning of the 20th century Szentgyorgyi Albert was among the first scientists who called the attention to the importance of flavin derivatives (Szentgyorgyi, Rusznyák : Nature 1936). He found, that they have functions like vitamins in the organism and called flavin vitamin P. He studied the permeability of arteries. Since then it has been clarified that flavin has no function like a vitamin, but its function is perhaps even more important. Eventually it was Szentgyorgyi and his colleagues who made basic research in connection with the physiological functions of flavin derivatives in Hungary.

Functions of flavin in human organism: All flavoproteins are enzymes without exception, so they actively take part in the metabolism of the organism. Certain flavoproteins function as enzymes linked with metals forming metalo-flavo-proteins. Flavin enzymes take part in the protein metabolism, breaking down of carbohydrates and digestion of fats. Without the presence of flavin derivatives biochemical circulation of three of the perhaps most important materials, proteins, carbohydrates and fats would be impossible in the organism.

Flavin derivatives linked to proteins are important cell synthesizers, they have a role in the synthesis of cells, first of all that of mitochondria of cells. Structure proteins of the membranes of mitochondria are mainly flavoproteins. In this role they are structure proteins and enzymes building up structures at the same time. As mitochondria ensure energy for the cells, energy supply of the organism is closely connected with the presence of flavin derivatives. Their deficiency or an even slightly lower level than the optimum result in adverse changes in protecting ability and making maximum use of energy in the organism. Flavin derivatives play furthermore an important part in the synthesizing of nucleotides (flavin-adenine-dinucleotide).

It is especially important to supply sportsmen with optimal flavin quantity. Their activity requires maximum energy to achieve maximum results. It should also be emphasized in case of the rising generation of sportsmen. In the developing organism increase of the amount of structure protein in proportion with the increase of the bulk of the body is essential. This double role requires a flavin intake of particularly high level.

Air-passengers and flavin derivatives It is well known, that before and during flights certain passengers are exposed to especially great mental and physical stress. In the state of stress making use of energy in the organism is increasing it can even multiply. It is important, that the flavin enzymes taking part in the energy supply of the organism function well. The control tests carried out in the last years show, that circulatory system problems can be significant during flights, in certain cases they can be severe (JAT LEG). It is useful to consume flavin derivatives to prevent these problems during stress.

Hungarian patent No. HU 200 915 describes a method for producing sweets or products of food industry with healing effects suitable for the prevention of passengers'illnesses in the state of art. Accordingly 3, 3-diphenyl-propyl-1-methyl- phenethyl-amine or one of its salt is mixed with a common carrier and additive of food industry products and the product is made into a chewing gum, soft drink or fruit juice containing 3, 3-diphenyl-propyl-1-methyl-phenethyl-amine or one of its salt in 0.01-0. 6 volume %.

Hungarian patent No. HU 197 510 makes known a method for making a product containing phenyl-alkyl-amine derivative against skeletal limb abnormalities. The product is made using processes of pharmaceutical-and food-industry making use of carrier, scenting, flavoring and coloring materials and other additives for producing sweet drops, filled drops, tablets, capsules, syrups, chewing gums. Their active substance is hydrogen atom or halogen atom in a compound of general formula. The product accompanying passengers is suitable for preventing'sea-sickness'during transportation.

When working out the solutions according to the invention we aimed to elaborate methods suitable for making sweet products ensuring flavin requirements of the organism, furthermore elaborating the sweet products suitable for the intake of flavin or flavin derivatives to the human organism.

When elaborating methods and sweet products according to the invention we realized, that in case liquid flavin or flavin derivatives of natural or synthetic origin are used for the products, from which jelly, powder or fluid of set concentration is produced and these are used for producing sweet products in given case sweetmeat, drops or chocolate known in themselves then the set aim can be achieved.

The invention is on the one hand a method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials, then a jelly is made with using proper additives and this jelly is used to produce sweet products.

In a preferred application of the method according to the invention additive used for jellification is saccharides and/or polysaccharide and/or polypeptide.

The invention is on the other hand a method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials and together with a solid or soft carrier are put into sweet products used as usual.

In a preferred application of the method according to the invention a carrier is ground grains, and/or meal made from false fruit e. g. apple-meal and flavin or flavin derivative is mixed to said carrier.

The invention is on the other hand a method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin used as raw materials are lyophilized and powder obtained this way is filled to sweet products in the usual way.

In a preferred application of the method according to the invention lyophilized flavin or flavin derivatives are mixed with solid or soft carriers or additives in given case with ground grains and/or meals made from false fruit e. g. apple-meal, or said lyophilized flavin or flavin derivatives are directly added to said sweet products.

The invention is on the other hand a method for making a sweet product suitable for ensuring flavin requirements of living organisms characterized by that, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials, concentration of said raw materials is set and liquid obtained this way is added to sweet products in the usual way.

In a preferred application of the method according to the invention liquid containing flavin of set concentration is mixed to a solid or soft carrier or additive to be used for making sweet products.

The invention is on the other hand a sweet product, preferably a sweetmeat of flavin content characterized by that, filling of said sweet product similar in appearance to sweetmeat marketed generally is a vegetal extract or flavin derivative synthesized by bacteria of high flavin content in liquid or jellied form.

In a preferred embodiment of the product according to the invention filling of said product is a fibrous organic material not causing chemical reaction with flavin, can not be digested, or can be digested with difficulty by the body. In another preferred embodiment of the product according to the invention there is another additive as well in said filling besides filling containing flavin, in given case fruit, for example sour cherry and/or raisin.

The invention is on the other hand a sweet product, preferably drops filled with flavin characterized by that said product similar to sweet products contains liquid or jellied flavin derivatives in different concentration and dosage (quantity).

The invention is on the other hand a sweet product, preferably chocolate filled with flavin characterized by that, said product similar to filled chocolates is a product filled with flavin jellied or mixed with carriers.

In a preferred embodiment of the product according to the invention said product is made in bars and/or bars divided into pieces and filling of said product contains flavin and is a flavored jelly and/or a fluid containing flavin derivatives mixed to another filling material or said filling is a dry flavin product made by lyofilization or by other drying methods used as usual.

In another preferred embodiment of the product according to the invention said product preferably contains carriers, additives, gelatinizing material used mainly in food industry. In a further preferred embodiment product contains filling materials suitable for use in food industry in given case honey, furthermore carriers suitable for the intake of flavin, in given case apple-meal, ground nuts, almond, ground grains and carrier material contains in given case alcohol and flavoring materials.

In another preferred embodiment of the product according to the invention flavin closed in a visible structure is dry or solved in a solvent or closed in a nanocapsule. In case of fluids containing flavin, flavin derivatives are advantageously present in said fluid in a soluble state or linked with a carrier cell, or cell scrap in a suspended state.

In another preferred embodiment of the product according to the invention said product is produced in a diabetic version for diabetics and elderly people being in more endangered status. The product contains flavin or flavin derivatives advantageously in dosed form.

In a preferred application of a method according to the invention the key point of the method according to the invention is the intake of flavin, respectively flavin derivatives (flavinoides) into sweet products. Flavin derivatives have more than a thousand types with several substitutions. Their common feature is, that they can be synthesized by plants, but they can be synthesized artificially as well. During using methods according to the invention, liquid flavin or flavin derivatives of natural or synthetic origin are used as raw materials, then a jelly is made with using proper additives. This additive can be saccharides, polysaccharide or polypeptide or the flavin is put on a solid carrier.

Any additive or carrier can be applied that does not cause chemical reaction with the flavin, does not prevent its absorption and is not harmful for the organism. A wide range of carriers, additives, gelatinizing materials used in food industry can be applied, furthermore filling materials used in food industry e. g. honey can also be used. In further preferred applications of the methods according to the invention not only a jelly is made, but a carrier, respectively a filling material, for example apple- meal, nuts, ground peanut, ground grains can be applied ensuring intake of flavin into the organism.

During the main applications of the method according to the invention gelation is made either with the additive, or with mixing to the carrier, for example ground grains, meals made from false-fruit, e. g. flavin is added to apple-seed meal. In one of the applications of the methods according to the invention liquid flavin or flavin derivatives are put on solid or soft carrier or additive and this is filled into sweet products in the known way. In another application concentration of liquid flavin is set to the required level and is added to sweet products e. g. sweetmeat, drops, chocolate as usually applied.

In case of the method according to the invention it is advantageous if intake of flavin derivatives into the organism takes place together with chocolate, which is easily accessible for the organism, still ensures high energy level. It is preferable if flavin derivatives are used corresponding with the environmental requirements closed into the'grid structure'of polysaccharide fibres in a form easily mobilized for the metabolism still free of danger of leaking.

Some preferable embodiments of the sweet products according to the invention: Sweetmeat flavin: It is a product similar in appearance to the generally marketed sweetmeat. The fact should be emphasized, that a diabetical version should be made as well, because diabetics and elderly people are endangered to a higher extent. Special features are ensured by its contents, the filling material. The filling is a liquid or gelatinized form of vegetal extract of high flavin content or flavin derivative synthesized by bacteria. It is advantageous for sportsmen and air-passengers, because flavin derivatives are present not in a liquid form, but in a semi-solid, jellied form, but containing flavin derivatives of the same biological value. Filling material does not cause chemical reaction with flavin, it is a fibrous material, that can not be digested or can only be digested with difficulty by the organism. The filling material of the sweetmeat can contain natural flavors as required but these can not bar absorption or cause chemical connection for the flavin derivatives.

Drops filled with flavin : Similarly to other sweet products it can contain liquid or gelatinized flavin derivatives in various concentration and dose (size). For sportsmen drops in doses for young children drops serving appraising objective as well can be applied. For air-passengers drops filled with gelatinized form is more advantageous, as it is safer in case of change of pressure. It can take over the role of the drops used for decades for improving opening of Eustachian tube stimulating swallowing during take-off and landing. In case advantages of consumption of flavin it can be sold at the airport or on board. Both possibilities are advantageous for both the passenger and the airline, because it protects health, which is good for the passenger and cuts the risk of harm to health resulting ftom flying and threatening insurance companies. One of the preferred embodiments of the drops is drops filled with liquid flavin.

Chocolate filled with flavin : Similarly to filled chocolates it is Sweet product gelatinized or mixed with carrier materials. It can be made in bars, or bars divided into several parts. Its filling material is a jelly containing flavin with flavoring and aromatic materials, a solution with flavin content mixed to other filling material, or a dry flavin product. Powder can be produced by liophylization or with other known drying technologies.

In case of sweet products of flavin content according to the invention they contain a defined dose of flavin in ready-to-consume state. Flavin content can be in liquid, jellied or mixture of carrier materials. Filling containing flavin is separated physically well from the form providing the structure (sweetmeat, drops, chocolate, their diabetic versions etc.). Flavin derivatives do not have chemical bond with the liquid, gelatinizing or other carrier materials. The concentration and volume of flavin closed in the structure can vary according to the certain products. The carrier material can contain alcohol and flavoring materials as required.

Flavin closed into a visible structure can be dry, a solution or closed into a nanocapsule. In case of fluids containing flavin, according to the invention flavin derivatives are present in the fluid in a soluble state or linked with a carrier cell, or cell scrap in a suspended state. In the products according to the invention other materials e. g. fruit (sour cherry) can be present besides flavin as well.

The advantage of the method and products according to the invention is, that the method is suitable for conditioning developing organisms, organisms under increased pressure, preventing disorders resulting from flavin deficiency. The products according to the invention are suitable for maintaining and improving the quality of life during physical treatments and chemotherapy accompanying or supplementing them.

Flavin derivatives serve monitoring and controlling of processes in the organism.

Food supplements in the form of sweet products (diabetic products as well) containing dosed flavin are especially recommended for young sportsmen, top sportsmen, ill persons and air-passengers. Flavin products are important components of structure proteins and enzymes of mitochondria in the organism. Flavin is indispensable for creative processes of the human organism and for producing energy, therefore they play an important role in preventing and curing illnesses. The advantage of the application of sweet products containing flavin is, that the consumer can consume a known quantity of flavin in a prepared form without devices or measuring equipment. Consumers can get flavin in similar quality to those flavin solutions marketed earlier.

The product according to the invention can evoke a pleasant feeling in the consumer due to the outer appearance of the drops, sweetmeat and chocolate. Dosed in liquid, jelly or mixed with other carrier materials in the hollow products it is a new form for contributing to preserving health and fighting against diseases arising due to flavin deficiency. The sweet product is also available for diabetics in diabetic form. It is also very important for air-passengers.

The product according to the invention can be advantageously used during long-haul flights, or long journeys by coach, or during long waiting, when remaining on a fixed place is necessary for a long time and there is no room for moving.