Title:
SYNERGIC COMBINATION OF 2,3-DIOXYGENASE INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR FOR THE TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/090850
Kind Code:
A1
Abstract:
The present invention provides a pharmaceutical composition for preventing or treating a cancer, which comprises a combination of a first compartment comprising a derivative having a certain cyclohexyl-ethylene-amino-heteroaryl moiety or pharmaceutically acceptable salt thereof as an active ingredient and a second compartment comprising an immune checkpoint inhibitor as an active ingredient. And, the present invention provides a method for treating a cancer in a mammal, which comprises administering a therapeutically effective amount of a derivative having a certain cyclohexyl-ethylene-amino-heteroaryl moiety or pharmaceutically acceptable salt thereof in combination with a therapeutically effective amount of an immune checkpoint inhibitor to the mammal in need thereof.
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Inventors:
LEE GYU-JIN (KR)
LEE EUI-CHUL (KR)
PARK SOL (KR)
LEE DONG-HOON (KR)
KIM SU-HWA (KR)
PARK JONG-SUK (KR)
KANG HO-WOONG (KR)
LEE EUI-CHUL (KR)
PARK SOL (KR)
LEE DONG-HOON (KR)
KIM SU-HWA (KR)
PARK JONG-SUK (KR)
KANG HO-WOONG (KR)
Application Number:
PCT/KR2022/018084
Publication Date:
May 25, 2023
Filing Date:
November 16, 2022
Export Citation:
Assignee:
YUHAN CORP (KR)
International Classes:
A61K31/4709; A61K9/00; A61K39/00; A61K39/395; A61K45/06; A61P35/00; C07K16/28
Domestic Patent References:
| WO2018039512A1 | 2018-03-01 | |||
| WO2016073770A1 | 2016-05-12 | |||
| WO2020233676A1 | 2020-11-26 |
Foreign References:
| CN109956927A | 2019-07-02 | |||
| KR102127125B1 | 2020-06-26 |
Attorney, Agent or Firm:
OH, Kook-Jin (KR)
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