Title:
TETRAHYDROFURAN-CONTAINING POLYCYCLIC DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/072096
Kind Code:
A1
Abstract:
Provided are a tetrahydrofuran-containing polycyclic derivative and a pharmaceutically acceptable salt thereof, and a preparation method therefor and the use thereof. In particular, provided are a compound as represented by general formula (I), a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing same, and the use thereof as a CDK2 inhibitor in the treatment of cancers.
Inventors:
ZHOU GUOQIANG (CN)
WEI YI (CN)
YUAN HONGBIN (CN)
LIU KUN CHIN (CN)
WEI YI (CN)
YUAN HONGBIN (CN)
LIU KUN CHIN (CN)
Application Number:
PCT/CN2022/127444
Publication Date:
May 04, 2023
Filing Date:
October 25, 2022
Export Citation:
Assignee:
ACERAND THERAPEUTICS HONG KONG LTD (CN)
International Classes:
C07D231/10; A61K31/395; A61K31/41; C07D207/30
Domestic Patent References:
| WO2022174031A1 | 2022-08-18 | |||
| WO2006087230A1 | 2006-08-24 |
Foreign References:
| US20050234059A1 | 2005-10-20 | |||
| CN1541208A | 2004-10-27 | |||
| CN107614499A | 2018-01-19 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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