Title:
THERAPEUTIC USE OF AZIRIDINO COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2003066806
Kind Code:
A3
Abstract:
Methods are provided for treatment of diseases. The methods include preventing or inhibiting transcription and/or replication of a nucleic acid molecule by administering to a subject in need of such treatment an effective amount of one or more aziridino compounds. Pharmaceutical compositions comprising the one or more aziridino compounds also are provided.
Inventors:
CHAPMAN JOHN (US)
ALFORD BERNADETTE (US)
PURMAL ANDREI A (US)
ZAVIZION BORIS (US)
ALFORD BERNADETTE (US)
PURMAL ANDREI A (US)
ZAVIZION BORIS (US)
Application Number:
PCT/US2002/035501
Publication Date:
December 24, 2003
Filing Date:
November 05, 2002
Export Citation:
Assignee:
VI TECHNOLOGIES INC (US)
CHAPMAN JOHN (US)
ALFORD BERNADETTE (US)
PURMAL ANDREI A (US)
ZAVIZION BORIS (US)
CHAPMAN JOHN (US)
ALFORD BERNADETTE (US)
PURMAL ANDREI A (US)
ZAVIZION BORIS (US)
International Classes:
C07D203/12; A61K9/19; A61K9/20; A61K9/28; A61K9/48; A61K9/52; A61K31/396; A61K45/00; A61K45/06; A61P1/04; A61P1/16; A61P3/10; A61P7/04; A61P7/06; A61P17/00; A61P17/06; A61P19/02; A61P19/04; A61P21/00; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P33/02; A61P35/00; A61P37/00; A61P37/06; A61P37/08; (IPC1-7): C12N7/06; A61K39/00; C12N7/00
Foreign References:
| US6093564A | 2000-07-25 | |||
| US6136586A | 2000-10-24 |
Other References:
See also references of EP 1451308A4
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