Title:
Tie2 ACTIVATOR, AGENT FOR MATURING, NORMALIZING OR STABILIZING BLOOD VESSELS, AGENT FOR STABILIZING LYMPHATIC VESSELS, PREPARATION FOR PREVENTING AND REDUCING WRINKLES, AND PREPARATION FOR REDUCING AND PREVENTING SWELLING
Document Type and Number:
WIPO Patent Application WO/2012/101747
Kind Code:
A1
Abstract:
Provided are a Tie2 activator, an agent for maturing, normalizing or stabilizing blood vessels and an agent for stabilizing lymphatic vessels, said agents comprising an extract of Lactuca indica and/or Chrysophyllum cainito Linn. Also provided are a preparation for preventing and reducing wrinkles and a preparation for reducing and preventing swelling, said preparations being characterized by containing said agent(s).
Inventors:
KAJIYA KENTARO (JP)
YAMANISHI HARUYO (JP)
NAKANO YUSUKE (JP)
YAMANISHI HARUYO (JP)
NAKANO YUSUKE (JP)
Application Number:
PCT/JP2011/051246
Publication Date:
August 02, 2012
Filing Date:
January 24, 2011
Export Citation:
Assignee:
SHISEIDO CO LTD (JP)
KAJIYA KENTARO (JP)
YAMANISHI HARUYO (JP)
NAKANO YUSUKE (JP)
KAJIYA KENTARO (JP)
YAMANISHI HARUYO (JP)
NAKANO YUSUKE (JP)
International Classes:
A61K36/28; A61K8/97; A61K36/00; A61K36/18; A61P7/10; A61P9/14; A61P17/00; A61Q19/08
Domestic Patent References:
| WO2010010248A2 | 2010-01-28 |
Foreign References:
| JP2002308753A | 2002-10-23 | |||
| JP2004323406A | 2004-11-18 | |||
| KR100897140B1 | 2009-05-14 | |||
| JP2001122732A | 2001-05-08 | |||
| JP2009114158A | 2009-05-28 |
Other References:
WANG, S. ET AL.: "Antioxidant Properties and Phytochemical Characteristics of Extracts from Lactuca indica.", J AGRIC FOOD CHEM, vol. 51, no. 5, 2003, pages 1506 - 1512
KIM, K.H. ET AL.: "Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro", BIOORG MED CHEM LETT, vol. 17, no. 24, 2007, pages 6739 - 6743
HOU, C. ET AL.: "Antidiabetic Dimeric Guianolides and a Lignan Glycoside from Lactuca indica", J NAT PROD, vol. 66, no. 5, 2003, pages 625 - 629
CHEN, Y. ET AL.: "Induction of Apoptosis by the Lactuca indica L. in Human Leukemia Cell Line and Its Active Components", J AGRIC FOOD CHEM, vol. 55, no. 5, 2007, pages 1743 - 1749
KIM, M. ET AL.: "Serum cholesterol-lowering effect of triterpene acetate obtained from Lactuca indica", SAENGYAK HAKHOECHI, vol. 28, no. 1, 1997, pages 21 - 25
EINBOND, L.S. ET AL.: "Anthocyanin antioxidants from edible fruits", FOOD CHEMISTRY, vol. 84, no. 1, 2004, pages 23 - 28
GITHIORI, J.B. ET AL.: "Use of plants in novel approaches for control of gastrointestinal helminths in livestock with emphasis on small ruminants", VETERINARY PARASITOLOGY, vol. 139, no. 4, 2006, pages 308 - 320
FUJIMAKI, Y. ET AL.: "Macrofilaricidal and microfilaricidal effects of Neurolaena lobata, a Guatemalan medicinal plant, on Brugia pahangi", JOURNAL OF HELMINTHOLOGY, vol. 79, no. 1, 2005, pages 23 - 28
KIM, K.H. ET AL.: "Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro", BIOORG MED CHEM LETT, vol. 17, no. 24, 2007, pages 6739 - 6743
HOU, C. ET AL.: "Antidiabetic Dimeric Guianolides and a Lignan Glycoside from Lactuca indica", J NAT PROD, vol. 66, no. 5, 2003, pages 625 - 629
CHEN, Y. ET AL.: "Induction of Apoptosis by the Lactuca indica L. in Human Leukemia Cell Line and Its Active Components", J AGRIC FOOD CHEM, vol. 55, no. 5, 2007, pages 1743 - 1749
KIM, M. ET AL.: "Serum cholesterol-lowering effect of triterpene acetate obtained from Lactuca indica", SAENGYAK HAKHOECHI, vol. 28, no. 1, 1997, pages 21 - 25
EINBOND, L.S. ET AL.: "Anthocyanin antioxidants from edible fruits", FOOD CHEMISTRY, vol. 84, no. 1, 2004, pages 23 - 28
GITHIORI, J.B. ET AL.: "Use of plants in novel approaches for control of gastrointestinal helminths in livestock with emphasis on small ruminants", VETERINARY PARASITOLOGY, vol. 139, no. 4, 2006, pages 308 - 320
FUJIMAKI, Y. ET AL.: "Macrofilaricidal and microfilaricidal effects of Neurolaena lobata, a Guatemalan medicinal plant, on Brugia pahangi", JOURNAL OF HELMINTHOLOGY, vol. 79, no. 1, 2005, pages 23 - 28
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Aoki 篤 (JP)
Aoki 篤 (JP)
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