Title:
TREATMENT PLANNING METHOD, TREATMENT PLANNING DEVICE, TREATMENT PLANNING PROGRAM AND METHOD FOR CALCULATING RELATIVE BIOLOGICAL EFFECTIVENESS
Document Type and Number:
WIPO Patent Application WO/2012/032609
Kind Code:
A1
Abstract:
[Problem] To provide a treatment planning method whereby a treatment plan, to which a modified microdosimetric kinetic model (MKM) is applied, can be derived within a short period of time.
[Solution] A treatment planning method which comprises using a modified MKM, i.e., a MKM having been modified for fitting to heavy particle beams, calculating a clinical dose that is expressed as a product of an absorption dose showing absorbed radiation energy and a relative biological effectiveness showing the extent of an effect of radiation on a living organism, and deriving a treatment plan by a three-dimensional spot scanning method with the use of the aforesaid clinical dose. Said treatment planning method involves: a weighted mean calculation step (S5) for calculating a dose-weighted mean of a saturation corrected dose-mean relative energy provided by multiple pencil beams affecting a position to be focused; a relative biological effectiveness calculation step (S6) for calculating the relative biological effectiveness on the basis of the dose-weighted mean of the saturation corrected dose-mean relative energy that is calculated above; and a clinical dose calculation step (S7) for calculating the clinical dose on the basis of the relative biological effectiveness that is calculated above.
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Inventors:
INANIWA TAKU (JP)
KASE YUKI (JP)
FURUKAWA TAKUJI (JP)
MATSUFUJI NARUHIRO (JP)
NODA KOJI (JP)
KASE YUKI (JP)
FURUKAWA TAKUJI (JP)
MATSUFUJI NARUHIRO (JP)
NODA KOJI (JP)
Application Number:
PCT/JP2010/065346
Publication Date:
March 15, 2012
Filing Date:
September 07, 2010
Export Citation:
Assignee:
NAT INST RADIOLOG (JP)
INANIWA TAKU (JP)
KASE YUKI (JP)
FURUKAWA TAKUJI (JP)
MATSUFUJI NARUHIRO (JP)
NODA KOJI (JP)
INANIWA TAKU (JP)
KASE YUKI (JP)
FURUKAWA TAKUJI (JP)
MATSUFUJI NARUHIRO (JP)
NODA KOJI (JP)
International Classes:
A61N5/10; G21K5/04
Foreign References:
| JP2009531138A | 2009-09-03 | |||
| JP2009525797A | 2009-07-16 |
Attorney, Agent or Firm:
ISONO Michizo (JP)
Michizo Isono (JP)
Michizo Isono (JP)
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Claims: