Title:
USE OF BACTEROIDES FRAGILIS IN IMPROVEMENT AND TREATMENT OF DIARRHEA
Document Type and Number:
WIPO Patent Application WO/2023/142877
Kind Code:
A1
Abstract:
Provided is the use of Bacteroides fragilis in the improvement and/or treatment of diarrhea. Tests of different mouse diarrhea models prove that Bacteroides fragilis ZY-312 with the deposit number of CGMCC No.10685 or inactivated Bacteroides fragilis ZY-312 has the effect of improving and treating diarrhea. The powder of the inactivated Bacteroides fragilis has a good effect of improving infectious diarrhea or non-infectious diarrhea in different concentrations of the formula, and has no side effects on the body.
Inventors:
LIU YANGYANG (CN)
WANG YE (CN)
ZHI FACHAO (CN)
ZHENG LIJUN (CN)
WANG WEI (CN)
CHANG XIUJUAN (CN)
LI PING (CN)
WANG YE (CN)
ZHI FACHAO (CN)
ZHENG LIJUN (CN)
WANG WEI (CN)
CHANG XIUJUAN (CN)
LI PING (CN)
Application Number:
PCT/CN2022/143593
Publication Date:
August 03, 2023
Filing Date:
December 29, 2022
Export Citation:
Assignee:
GUANGZHOU ZHIYI BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K35/741; A61P1/12; C12N1/20; C12R1/01
Foreign References:
| CN114558036A | 2022-05-31 | |||
| CN115252652A | 2022-11-01 | |||
| CN106399141A | 2017-02-15 | |||
| CN109481473A | 2019-03-19 | |||
| CN113730443A | 2021-12-03 | |||
| CN107625792A | 2018-01-26 |
Other References:
ZHANG WENDI, ZHU BO, XU JIAHUI, LIU YANGYANG, QIU ENQI, LI ZHIJUN, LI ZHENGCHAO, HE YAN, ZHOU HONGWEI, BAI YANG, ZHI FACHAO: "Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses", FRONTIERS IN IMMUNOLOGY, vol. 9, XP093081258, DOI: 10.3389/fimmu.2018.01040
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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