Title:
USE OF CTD-2256P15.2 AND ENCODING MICROPEPTIDE THEREOF AS TARGET IN DEVELOPMENT OF TUMOR TREATMENT DRUG
Document Type and Number:
WIPO Patent Application WO/2023/082242
Kind Code:
A1
Abstract:
Provided in the present invention is the use of CTD-2256P15.2 and an encoding micropeptide thereof as a target in the development of a tumor treatment drug. Further provided in the present invention are the following uses of a CTD-2256P15.2 inhibitor: 1) preparing a tumor treatment product; 2) preparing a product for reducing the drug resistance of tumor cells to a chemotherapeutic drug; and 3) preparing a product for improving the sensitivity of tumor cells to a chemotherapeutic drug.
Inventors:
TANG TIESHAN (CN)
GUO CAIXIA (CN)
ZHOU BO (CN)
ZHANG CHUANCHAO (CN)
YAO FUWEN (CN)
GU FENG (CN)
MA YONGJIE (CN)
GUO CAIXIA (CN)
ZHOU BO (CN)
ZHANG CHUANCHAO (CN)
YAO FUWEN (CN)
GU FENG (CN)
MA YONGJIE (CN)
Application Number:
PCT/CN2021/130604
Publication Date:
May 19, 2023
Filing Date:
November 15, 2021
Export Citation:
Assignee:
INST OF ZOOLOGY CHINESEACADEMY OF SCIENCES (CN)
BEIJING INSTITUTE OF GENOMICS CHINESE ACADEMY OF SCIENCES/CHINA NAT FOR BIOINFORMATION (CN)
TIANJIN MEDICAL UNIV CANCER INSTITUTE AND HOSPITAL (CN)
BEIJING INSTITUTE OF GENOMICS CHINESE ACADEMY OF SCIENCES/CHINA NAT FOR BIOINFORMATION (CN)
TIANJIN MEDICAL UNIV CANCER INSTITUTE AND HOSPITAL (CN)
International Classes:
C12Q1/6886; A61K31/713; A61K45/00; A61P35/00
Domestic Patent References:
| WO2017031993A1 | 2017-03-02 |
Foreign References:
| CN109010831A | 2018-12-18 | |||
| CN113201591A | 2021-08-03 |
Other References:
ZHANG YONG, LIAO GAOMING, BAI JING, ZHANG XINXIN, XU LIWEN, DENG CHUNYU, YAN MIN, XIE AIMIN, LUO TAO, LONG ZHILIN, XIAO YUN, LI XI: "Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers", MOLECULAR THERAPY-NUCLEIC ACIDS, CELL PRESS, US, vol. 17, 1 September 2019 (2019-09-01), US , pages 362 - 373, XP093065947, ISSN: 2162-2531, DOI: 10.1016/j.omtn.2019.05.030
ZHOU ZHEN-XU, CHEN XIAO-MING, ZHANG YU-QI, PENG LIU, XUE XIANG-YANG, LI GUO-XIN: "Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissues", CELL DEATH AND DISEASE, vol. 40, no. 2, 28 February 2020 (2020-02-28), XP093065953, ISSN: 0144-8463, DOI: 10.1042/BSR20191139
ZHOU ZHEN-XU, CHEN XIAO-MING, ZHANG YU-QI, PENG LIU, XUE XIANG-YANG, LI GUO-XIN: "Comprehensive analysis of long noncoding RNA and mRNA in five colorectal cancer tissues and five normal tissues", CELL DEATH AND DISEASE, vol. 40, no. 2, 28 February 2020 (2020-02-28), XP093065953, ISSN: 0144-8463, DOI: 10.1042/BSR20191139
Attorney, Agent or Firm:
JEEKAI&PARTNERS (CN)
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