Title:
USE OF NICOTINAMIDE NUCLEOSIDE ARYL FORMATE COMPOUND AND COMPOSITION THEREOF, AND COMPOUND CRYSTAL FORM
Document Type and Number:
WIPO Patent Application WO/2022/022472
Kind Code:
A1
Abstract:
Use of a nicotinamide nucleoside triaryl formate compound and a composition thereof in increasing the level of coenzyme I (NAD) in a human body, improving a health condition or treating a related disease, and a compound of formula (II-1) in a crystal form. The structure of the nicotinamide nucleoside triaryl formate compound is represented by formula (I). As a synthetic precursor of the NAD, compared with nicotinamide nucleoside, the nicotinamide nucleoside triaryl formate compound not only can effectively increase the level of NAD in a human body, but also is easier to prepare, has the significantly reduced cost, and has a significant industrial application advantage.
Inventors:
GAO ZHILING (US)
HUANG QIANG (CN)
HUANG QIANG (CN)
Application Number:
PCT/CN2021/108490
Publication Date:
February 03, 2022
Filing Date:
July 26, 2021
Export Citation:
Assignee:
GAO ZHILING (US)
HUANG QIANG (CN)
HUANG QIANG (CN)
International Classes:
A61K31/706; A23L33/10; A23L33/105; A61P1/16; A61P3/00; A61P3/04; A61P3/10; A61P9/04; A61P9/12; A61P21/00; A61P25/16; A61P25/28; A61P31/18; A61P31/20; A61P35/00; A61P39/06; C07H1/00; C07H1/06; C07H19/048
Domestic Patent References:
| WO2019122084A1 | 2019-06-27 |
Foreign References:
| CN106715455A | 2017-05-24 | |||
| US20180227168A1 | 2018-08-09 |
Attorney, Agent or Firm:
BEIJING TANLULAI PATENT AGENT LTD et al. (CN)
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