Title:
USE OF SEX HORMONES TO OBTAIN A NASAL PHARMACEUTICAL COMPOSITION THAT IS USEFUL IN THE TREATMENT OF UNDESIRABLE UTERINE BLEEDING
Document Type and Number:
WIPO Patent Application WO2000059447
Kind Code:
A3
Abstract:
The invention relates to the use of a sex hormone (in particular estradiol on its own or with noresthisterone combined with methyl cyclodextrine) to obtain a pharmaceutical composition that is suitable for nasal administration in order to treat undesirable uterine bleeding phenomena in women.
Inventors:
TSOUDEROS YANNIS (FR)
Application Number:
PCT/FR2000/000790
Publication Date:
April 26, 2001
Filing Date:
March 30, 2000
Export Citation:
Assignee:
ADIR (FR)
TSOUDEROS YANNIS (FR)
TSOUDEROS YANNIS (FR)
International Classes:
A61K9/00; A61K31/565; A61K9/08; A61K31/567; A61K45/06; A61K47/02; A61K47/40; A61P15/00; C07J1/00; (IPC1-7): A61K31/565; A61K31/57
Domestic Patent References:
| WO1998003207A1 | 1998-01-29 | |||
| WO1997046574A1 | 1997-12-11 |
Foreign References:
| US4383993A | 1983-05-17 | |||
| EP0349091A1 | 1990-01-03 |
Other References:
KARTHAUS M. ET AL: "Acute abdomen due to endometriosis as a diagnostic and therapeutic challenge in the treatment of acute myelocytic leukemia.", ANNALS OF HEMATOLOGY, (1997) 74/1 (29-31)., XP000856615
BAYER S.R. ET AL: "Clinical manifestations and treatment of dysfunctional uterine bleeding.", JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, (1993) 269/14 (1823-1828)., XP000856624
BRUN J.L.: "[Management of uterine bleeding in 1994]. LE POINT SUR LE TRAITEMENT DES MENOMETRORRAGIES EN 1994.", CONTRACEPTION FERTILITE SEXUALITE, (1994) 22/3 (147-151)., XP000856625
NILLIUS S.J.: "LH-RH nasal spray in contraception Future Aspects in Contraception. International Symposium. Heidelberg 5-8 September 1984.", CONTRACEPT. DELIV. SYST., (1984) 5/3 (36)., XP000856854
COLL CAPDEVILA C: "Dysfunctional uterine bleeding and dysmenorrhea.", EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, (1997 DEC) 2 (4) 229-37. REF: 28, XP000856691
BRENNER, PAUL F. ET AL: "Ovulation inhibition with nafarelin acetate nasal administration for six months", CONTRACEPTION (1985), 32(6), 531-51, XP000856801
BAYER S.R. ET AL: "Clinical manifestations and treatment of dysfunctional uterine bleeding.", JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, (1993) 269/14 (1823-1828)., XP000856624
BRUN J.L.: "[Management of uterine bleeding in 1994]. LE POINT SUR LE TRAITEMENT DES MENOMETRORRAGIES EN 1994.", CONTRACEPTION FERTILITE SEXUALITE, (1994) 22/3 (147-151)., XP000856625
NILLIUS S.J.: "LH-RH nasal spray in contraception Future Aspects in Contraception. International Symposium. Heidelberg 5-8 September 1984.", CONTRACEPT. DELIV. SYST., (1984) 5/3 (36)., XP000856854
COLL CAPDEVILA C: "Dysfunctional uterine bleeding and dysmenorrhea.", EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, (1997 DEC) 2 (4) 229-37. REF: 28, XP000856691
BRENNER, PAUL F. ET AL: "Ovulation inhibition with nafarelin acetate nasal administration for six months", CONTRACEPTION (1985), 32(6), 531-51, XP000856801
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