Title:
VACCINE COMPOSITION COMPRISING INACTIVATED PNEUMOCOCCAL MUTANT STRAIN
Document Type and Number:
WIPO Patent Application WO/2023/121036
Kind Code:
A1
Abstract:
The present application relates to a vaccine composition comprising an inactivated pneumococcal mutant strain for prevention or treatment of pneumonia, wherein the inactivated pneumococcal mutant strain has a part or the entirety of the pep27 gene deleted.
Inventors:
LEE DONG KWON (KR)
SHIN HEA LYUNG (KR)
LEE KYUNG MOON (KR)
KWON SO HYUN (KR)
BAEK JONG HYUK (KR)
SHIN HEA LYUNG (KR)
LEE KYUNG MOON (KR)
KWON SO HYUN (KR)
BAEK JONG HYUK (KR)
Application Number:
PCT/KR2022/019299
Publication Date:
June 29, 2023
Filing Date:
November 30, 2022
Export Citation:
Assignee:
ILDONG PHARMACEUTICAL CO LTD (KR)
International Classes:
A61K39/09; A61K9/19; A61K39/00; A61K47/22; A61K47/26; A61K47/46; A61P31/04; C12N1/20
Domestic Patent References:
| WO2013043643A1 | 2013-03-28 |
Foreign References:
| KR20120010906A | 2012-02-06 | |||
| KR102040665B1 | 2019-11-06 |
Other References:
KIM GYU-LEE; CHOI SANG-YOON; SEON SEUNG-HAN; LEE SEUNGYEOP; PARK SANG-SANG; SONG JOON YOUNG; BRILES DAVID E.; RHEE DONG-KWON: "Pneumococcalpep27mutant immunization stimulates cytokine secretion and confers long-term immunity with a wide range of protection, including against non-typeable strains", VACCINE, ELSEVIER, AMSTERDAM, NL, vol. 34, no. 51, 16 November 2016 (2016-11-16), AMSTERDAM, NL , pages 6481 - 6492, XP029824260, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2016.10.071
CHOI SANG-YOON, TRAN THAO DANG-HIEN, BRILES DAVID E., RHEE DONG-KWON: "Inactivated pep27 mutant as an effective mucosal vaccine against a secondary lethal pneumococcal challenge in mice", CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, vol. 2, no. 1, 1 January 2013 (2013-01-01), pages 58 - 65, XP055844815, ISSN: 2287-3651, DOI: 10.7774/cevr.2013.2.1.58
CHOI SANG-YOON, TRAN THAO DANG-HIEN, BRILES DAVID E., RHEE DONG-KWON: "Inactivated pep27 mutant as an effective mucosal vaccine against a secondary lethal pneumococcal challenge in mice", CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, vol. 2, no. 1, 1 January 2013 (2013-01-01), pages 58 - 65, XP055844815, ISSN: 2287-3651, DOI: 10.7774/cevr.2013.2.1.58
Attorney, Agent or Firm:
SEOHAN INTELLECTUAL PROPERTY LAW FIRM (KR)
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