VITAMIN D¿3? DERIVATIVES AND REMEDIES FOR INFLAMMATORY RESPIRATORY DISEASES PREPARED FROM THE SAME

Title:

VITAMIN D¿3? DERIVATIVES AND REMEDIES FOR INFLAMMATORY RESPIRATORY DISEASES PREPARED FROM THE SAME

Document Type and Number:

WIPO Patent Application WO/1998/058909

Kind Code:

A1

Abstract:

Vitamin D¿3? derivatives represented by general formula [1] and a process for producing the same: wherein R¿1? and R¿2? represent each hydrogen, trialkylsilyl, etc.; R¿3? and R¿4? represent each hydrogen, hydroxy, etc.; R¿5? to R¿8? represent each hydrogen, hydroxy, alkyl or acyloxy; R¿9? represents hydrogen, hydroxy, alkyl or alkylthio; R¿10? represents hydrogen, alkyl or alkyloxy; A and B represent each hydrogen, hydroxy, etc.; X and Y represent each carbonyl oxygen, or one of X and Y represents hydrogen while another represents hydroxy, etc.; and n and m are each 0 to 2. These compounds are usable as the active ingredients of remedies for inflammatory respiratory diseases, malignant tumors, articular rheumatism, osteoporosis, diabetes mellitus, hypertension, baldness, acne, psoriasis, and dermatitis.

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JP2000053639

PRODUCTION OF ACTIVATED VITAMIN D DERIVATIVE

Inventors:

TANAKA HIROKO (JP)
GAO QINGZHI (JP)
MANABE KENJI (JP)
FURUYA MINORU (JP)
TABE MASAYASU (JP)
ISHIZUKA SEIICHI (JP)
CHOKKI MANABU (JP)
MITSUHASHI HIROAKI (JP)
KISHIMOTO TADASHI (JP)
HAZATO ATSUO (JP)
SAKUMA YASUJI (JP)

Application Number:

PCT/JP1998/002813

Publication Date:

December 30, 1998

Filing Date:

June 24, 1998

Export Citation:

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Assignee:

TEIJIN LTD (JP)
TANAKA HIROKO (JP)
GAO QINGZHI (JP)
MANABE KENJI (JP)
FURUYA MINORU (JP)
TABE MASAYASU (JP)
ISHIZUKA SEIICHI (JP)
CHOKKI MANABU (JP)
MITSUHASHI HIROAKI (JP)
KISHIMOTO TADASHI (JP)
HAZATO ATSUO (JP)
SAKUMA YASUJI (JP)

International Classes:

C07C401/00; (IPC1-7): C07C401/00; A61K31/59

Foreign References:

JPH0853411A	1996-02-27
JPH03504377A	1991-09-26

Other References: