Title:
WNT-1 RELATED POLYPEPTIDES, AND NUCLEIC ACIDS ENCODING THE SAME
Document Type and Number:
WIPO Patent Application WO2001070775
Kind Code:
A3
Abstract:
An isolated Wnt-1 related polypeptide comprising an amino acid sequence having at least 80% sequence identity to the sequence of SEQ ID NOS: 1, 3, 5, or 7 polynucleotides encoding these peptides,and antibodies to the polypeptides are useful in treating cancers
Inventors:
RASTELLI LUCA K (US)
PENNICA DIANE (US)
PENNICA DIANE (US)
Application Number:
PCT/US2001/009600
Publication Date:
January 10, 2002
Filing Date:
March 22, 2001
Export Citation:
Assignee:
CURAGEN CORP (US)
GENENTECH INC (US)
RASTELLI LUCA K (US)
PENNICA DIANE (US)
GENENTECH INC (US)
RASTELLI LUCA K (US)
PENNICA DIANE (US)
International Classes:
A01K67/027; A61K31/7088; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P9/10; A61P35/00; A61P43/00; C07K14/00; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12Q1/02; C12Q1/68; (IPC1-7): C07K14/47; C12N15/12; C07K16/18; C12N5/10; A01K67/027; C12Q1/68
Other References:
[online] 3 March 2000 (2000-03-03), MARRA ET AL: "The WashU-HHMI mouse EST project", XP002177851, retrieved from EMBL accession no. AA966965
DIANE PENNICA ET AL: "WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1 transformed cells and aberrantly expressed in human colon tumors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 95, no. 25, December 1998 (1998-12-01), pages 14717 - 14722, XP002105893, ISSN: 0027-8424
[online] 29 September 2000 (2000-09-29), KAWAKAMI ET AL.: "NEDO human cDNA sequencing project", XP002177852, retrieved from EMBL accession no. AK027111
DIANE PENNICA ET AL: "WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1 transformed cells and aberrantly expressed in human colon tumors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 95, no. 25, December 1998 (1998-12-01), pages 14717 - 14722, XP002105893, ISSN: 0027-8424
[online] 29 September 2000 (2000-09-29), KAWAKAMI ET AL.: "NEDO human cDNA sequencing project", XP002177852, retrieved from EMBL accession no. AK027111
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