Title:
ZINC-BINDER BASED EBNA1-SPECIFIC COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2019/141246
Kind Code:
A1
Abstract:
The present disclosure relates to compounds useful in the treatment, imaging, and/or diagnosis of Epstein-Barr virus (EBV)-positive cells, such as cancer.
Inventors:
WONG KA LEUNG (CN)
MAK NAI KI (CN)
JIANG LIJUN (CN)
MAK NAI KI (CN)
JIANG LIJUN (CN)
Application Number:
PCT/CN2019/072375
Publication Date:
July 25, 2019
Filing Date:
January 18, 2019
Export Citation:
Assignee:
UNIV HONG KONG BAPTIST UNIV (CN)
International Classes:
C07C15/52; C07C229/56; C07K14/05
Other References:
JIANG, LIJUN ET AL.: "EBNA1 specific luminescence small molecules for imaging and inhibition of latently EBV-infected tumor cells", CHEM. CUMMUN., vol. 50, 28 March 2014 (2014-03-28), pages 6517 - 6519, XP055434176
JIANG, LIJUN ET AL.: "EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus", NATURE BIOMEDICAL ENGINEERING, vol. 1, 13 March 2017 (2017-03-13), pages 1 - 10, XP055581058, doi:10.1038/s41551-017-0042
JIANG, LIJUN ET AL.: "EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus", NATURE BIOMEDICAL ENGINEERING, vol. 1, 13 March 2017 (2017-03-13), pages 1 - 10, XP055581058, doi:10.1038/s41551-017-0042
Attorney, Agent or Firm:
BEIJING PAT SF INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)
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