Title:
AN ANTRODIA CAMPHORATA CYCLOHEXENONE COMPOUND USED FOR DECREASING PHYSIOLOGICAL FATIGUE
Document Type and Number:
WIPO Patent Application WO/2009/000168
Kind Code:
A1
Abstract:
Antrodia camphorata cyclohexenone compounds used for decreasing physiological fatigue, in particular 4-hydroxy-2,3-dimethoxy-6-methy-5[3,7,11-trimethy- dodeca-2,6,10-trienyl]-cyclohex-2-enone isolated from extract of Antrodia camphorata, are capable of decreasing physiological fatigue effectively. In the present invention, administration of said compounds immediately after highly intensive prostrate physical exercises with 80% maximal oxygen uptake can increase the metabolism of creatine kinase and blood ammonia and militate to recover their concentration, thus to achieve the effect of decreasing physiological fatigue.
Inventors:
LIU SHENG-YUN (CN)
WEN WU-CHE (CN)
KUO MAO-TIEN (CN)
WEN WU-CHE (CN)
KUO MAO-TIEN (CN)
Application Number:
PCT/CN2008/070395
Publication Date:
December 31, 2008
Filing Date:
March 03, 2008
Export Citation:
Assignee:
GOLDEN BIOTECHNOLOGY CORP (CN)
LIU SHENG-YUN (CN)
WEN WU-CHE (CN)
KUO MAO-TIEN (CN)
LIU SHENG-YUN (CN)
WEN WU-CHE (CN)
KUO MAO-TIEN (CN)
International Classes:
C07C49/753; A61K31/122; A61K36/07; A61P35/00; C07C321/22
Foreign References:
| CN1666982A | 2005-09-14 | |||
| US7342137B1 | 2008-03-11 |
Other References:
CHERNG I.-H. ET AL.: "Three new triterpenoids from Antrodia cinnamomea", JOURNAL OF NATURAL PRODUCTS, vol. 58, no. 3, 1995, pages 365 - 371, XP008138391
CHEN C.-H. ET AL.: "New Steroid Acids from Antrodia Cinnamomea a Fungal Parasite of Cinnamomum micranthum", JOURNAL OF NATURAL PRODUCTS, vol. 58, no. 11, 1995, pages 1655 - 1661, XP008138392, DOI: doi:10.1021/np50125a002
CHIANG H.-C. ET AL.: "A sesquiterpene lactone, phenyl compounds from Antrodia cinnamomea", PHYTOCHEMISTRY, vol. 39, no. 3, 1995, pages 613 - 616, XP008138393, DOI: doi:10.1016/0031-9422(95)00025-3
YANG S.-W. ET AL.: "Steroids and triterpenoids of Antrodia cinnamomea-a fungus parasitic on Cinnamomum microanthus", PHYTOCHEMISTRY, vol. 41, no. 5, 1996, pages 1389 - 1392, XP008138394
CHENG I.-H. ET AL.: "Triterpenoids from Antrodia cinnamomea", PHYTOCHEMISTRY, vol. 41, no. 1, 1996, pages 263 - 267
CHEN C.-H. ET AL.: "New Steroid Acids from Antrodia Cinnamomea a Fungal Parasite of Cinnamomum micranthum", JOURNAL OF NATURAL PRODUCTS, vol. 58, no. 11, 1995, pages 1655 - 1661, XP008138392, DOI: doi:10.1021/np50125a002
CHIANG H.-C. ET AL.: "A sesquiterpene lactone, phenyl compounds from Antrodia cinnamomea", PHYTOCHEMISTRY, vol. 39, no. 3, 1995, pages 613 - 616, XP008138393, DOI: doi:10.1016/0031-9422(95)00025-3
YANG S.-W. ET AL.: "Steroids and triterpenoids of Antrodia cinnamomea-a fungus parasitic on Cinnamomum microanthus", PHYTOCHEMISTRY, vol. 41, no. 5, 1996, pages 1389 - 1392, XP008138394
CHENG I.-H. ET AL.: "Triterpenoids from Antrodia cinnamomea", PHYTOCHEMISTRY, vol. 41, no. 1, 1996, pages 263 - 267
Attorney, Agent or Firm:
DRAGON INTELLECTUAL PROPERTY LAW FIRM (Bldg.2 No.32Xizhimen North Street,,Haidian District, Beijing 2, CN)
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