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WO/2021/247024A1 |
An implantable scaffold structure includes a biodegradable metallic scaffold; an inner non- biodegradable polymer coating conformally covering the scaffold; an outer coating formed of a biodegradable or non-biodegradable polymer, and hav...
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WO/2021/242835A1 |
The present disclosure provides extruded PTFE composite tubes with a reduced coefficient of friction (COF). In some embodiments, such extruded PTFE composite tubes may exhibit a reduced change in coefficient of friction between about 20Â...
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WO/2021/240254A1 |
Polymeric tubing containing extractable component(s) for use in medical articles include a tube and a vapor-deposited coating of a barrier polymer covering at least a portion of the tube. The barrier polymer is derived from at least one ...
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WO/2021/242783A1 |
Devices, systems, and methods are provided including a structure having one or more surfaces configured for internal use within a patient's body and one or more therapeutic compositions comprising one or more active substances including ...
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WO/2021/242174A1 |
Disclosed herein are compounds in the form of polymers, oligomers and defined molecules having repeating units that all incorporate repeating units formed from an imidazolium group and a biodegradable chain connected to an adjacent repea...
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WO/2021/234131A1 |
Coatings for medical devices having selectable levels of durability and lubricity are disclosed. The coatings include polymeric material components, the characteristics and relative amounts of which can be selected to provide target leve...
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WO/2021/233743A1 |
The disclosure relates to a coating composition comprising a polymerizable compound of formula [1], wherein G is a residue of a hydrophobic hydroxy-functional oligomer, n is 1-10, each R1 independently is a residue of a C6-C20 aliphatic,...
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WO/2021/236248A1 |
A medical device may include a body and a photosensitizer integrated with the body. The medical device may passively resist colonization of bacteria under ambient light. The medical device may also actively resist colonization of bacteri...
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WO/2021/228289A1 |
The present invention relates to a random terpolymer of N-(2-hydroxypropyl) methacrylamide, carboxybetaine methacrylamide and sulfobetaine methacrylamide, to a polymer brush and to a functionalized polymer brush containing this terpolyme...
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WO/2021/225443A1 |
The invention relates to the field of polymers, in particular to polymer systems based on polyurethane (PU) having a broad spectrum biocidal activity and the use thereof in the manufacture of biocidal products. Provided is a process to p...
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WO/2021/224479A1 |
The invention relates to a medical device delivery system comprising a catheter shaft having a proximal end and a distal end portion; an expandable member provided at the distal end portion of the shaft, the expandable member having a de...
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WO/2021/224321A1 |
The present invention relates to an implant, comprising at least one three-dimensional porous structural element that consists of at least one synthetic polymer, the at least one porous structural element being irreversibly connected to ...
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WO/2021/217242A1 |
A steerable catheter may include an elongate shaft member and a braided reinforcement structure embedded into a wall of the elongate shaft member. The braided reinforcement structure may include a first braided portion including a first ...
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WO/2021/207082A2 |
The invention relates to the field of phage therapy and is particularly directed at providing a phage-based composition and method for treating or preventing infections associated with implantable devices. The composition may be directly...
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WO/2021/207331A1 |
Embodiments relate to a crosslinked citrate-based elastomer catheter that is biodegradable and kink resistant. Embodiments of the crosslinked citrate-based elastomer material swells when surrounded by fluid (body fluid) so as to anchor t...
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WO/2021/198495A1 |
The present invention relates to a coating for a device, wherein the coating comprises a polymeric film, wherein the polymeric film comprises a polymerisation product formed from a polymerisation solution comprising dopamine, or a salt t...
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WO/2021/202709A1 |
A method includes mixing a liquid carrier and a powder formulation including an S-nitrosothiol (RSNO) powder to form a nitric oxide generating solution; and within a predetermined time of mixing, introducing the nitric oxide generating s...
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WO/2021/188178A1 |
Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Add...
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WO/2021/183718A1 |
Catheters (50) including thermoplastic polyurethane polymer tubing (60) with improved shape recovery after storage in a substantially coiled configuration are provided.
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WO/2021/178785A1 |
Packaging for hydrated articles are generally provided. In some embodiments, packaged articles are provided. For example, in some embodiments, a container contains an article such as a catheter and/or polymeric material. The disclosed pa...
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WO/2021/171849A1 |
A medical shaft (1) has: a shaft (10) provided with at least one lumen (11) extending in the longitudinal direction; a core member (20) positioned in the lumen (11), the core member (20) extending along the longitudinal direction; and a ...
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WO/2021/171032A1 |
The present invention relates to antimicrobial materials comprising copper and zinc incorporated into or coated on a substrate material, wherein the substrate comprises a rubber component. The present invention also relates to methods of...
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WO/2021/168389A1 |
The present disclosure relates to methods of manufacture, apparatus, and fixtures. An apparatus comprising an inner liner having a hollow chamber extending the length of the inner liner, at least two guide rings disposed collectively alo...
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WO/2021/168284A1 |
Various embodiments disclosed relate to polymer-encapsulated drug particles and a drug-releasing coating including the same, as well as drug-coated balloon catheters for treating, preventing, or reducing the recurrence of strictures in b...
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WO/2021/160788A1 |
Methods for reducing or preventing colloids adhesion and/or fouling on different substrates, compositions, and copolymers useful therefor The present invention relates to a method for reducing or preventing colloids adhesion and/or fouli...
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WO/2021/161816A1 |
The purpose of the present invention is to provide an antibacterial molded article of which the antibacterial performance can be further improved. The present invention for achieving the purpose relates to an antibacterial molded article...
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WO/2021/160625A1 |
The present invention relates to a medical device suitable for being inserted into the lumen of an anatomic structure of a subject, said medical device comprising means for administration of TRPC6 inhibitor, wherein said means comprises ...
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WO/2021/155248A1 |
Disclosed is a bioresorbable implant with enhanced bone ingrowth and tissue integration utilizing an inside-out resorption mechanism and a method to manufacture a bioresorbable implants for use in osteotomies and bone-soft tissue reconst...
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WO/2021/155303A1 |
An antimicrobial coating is formed from a biocompatible flexible polymer having incorporated therein an active material having a reducible form of silver, where at least a portion of the active material is exposed at the surface of the p...
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WO/2021/150401A1 |
A catheter assembly 10, comprising: a catheter adapter 12, comprising a distal end 14, a proximal end 16, and a lumen 18 extending through the distal end of the catheter adapter and the proximal end of the catheter adapter; a catheter 20...
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WO/2021/096925A9 |
The present disclosure is directed toward drug coated balloons, and in particular to drug coated balloons having a drug coating layer that primarily uses therapeutic agents alone for improving the quality of treatments in which drug coat...
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WO/2021/144769A1 |
A composition, comprising: a physiologically-acceptable polydimethylsiloxane having a surface; and one or more normal C6-C20NR1R2 saturated amine, salt thereof, or combination thereof, in contact with the polydimethylsiloxane, the surfac...
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WO/2021/145249A1 |
This method for producing a medical device having a base material and a hydrophilic polymer layer includes a step for heating, at 50-100°C, a solution containing: a base material placed in an alkaline solution and pretreated at 50-100°...
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WO/2021/144142A1 |
A method for introducing a soft metal into a hard coating during a physical vapor deposition process. The method including steps of providing a substrate; depositing a bonding layer on the substrate; and depositing the hard coating on th...
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WO/2021/142391A1 |
Fouling on the surface of biomaterials and medical devices by proteins and microorganisms in the body severely hinders device functionality and drastically shortens lifetime. Currently, there is high demand for coatings that mitigate thi...
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WO/2021/141545A1 |
Disclosed herein is a composite material suitable for inhibiting biofilm growth, the composite material comprising a substrate material and a random copolymeric material covalently bonded to a surface of the substrate material. The rando...
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WO/2021/136765A1 |
It is provided a composition comprising phytic acid or a pharmaceutically acceptable salt thereof, for use in reducing or preventing microorganisms' proliferation and/or encrustations caused by a urinary tract device implanted in a subje...
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WO/2021/138156A1 |
A method for preventing and treating internal infections, e.g., urinary tract infections, caused by catheters is provided, in particular by reduction in catheter-associated biofilms. A coating composition is used to treat the catheter an...
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WO/2021/133762A1 |
A profile includes: a sidewall, a lumen for a fluid path, and an end, the profile including a thermoset material, wherein the profile includes a sealed end without an external bonding material, wherein the sealed end withstands a seal in...
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WO/2021/132628A1 |
The present invention addresses the problem of discovering cerium oxide nanoparticles having high oxidation performance and a dispersion including the same. Provided are cerium oxide nanoparticles and a dispersion including the same, the...
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WO/2021/132643A1 |
The present invention addresses the problem of finding: cerium oxide nanoparticles having high oxidation performance and anti-oxidation performance; and a dispersion which contains the cerium oxide nanoparticles. The present invention pr...
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WO/2021/126084A1 |
Disclosed herein is a composite material comprising a substrate coated with a block copolymer brush, where the block copolymer brush comprises a first block of a hydrophobic polymer conjugated to a nitric oxide source, where the first bl...
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WO/2021/126904A1 |
The present application relates generally to tubes, such as thin walled catheter liners with small wall thicknesses (e.g., less than 1 mm), comprising crosslinked fluoropolymers, e.g., crosslinked poly(tetrafluoroethylene). The disclosur...
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WO/2021/127040A1 |
Medical products including hydrophilic coating containing silver antimicrobial, hydration medium and a stabilizing agent.
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WO/2021/124206A1 |
A surface modifying coating for an article that includes a first component having a surface in frictional engagement with a surface of a second component. At least a portion of a surface of one of the components is coated with a coating ...
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WO/2021/123126A1 |
The present invention relates to a method for preparation of a functionalized surface comprising the steps: a) coating of a carrier with a least one polymer selected from a polyanionic or polycationic polymer, b) addition of at least one...
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WO/2021/122822A1 |
The present invention relates to a catheter device comprising at least one pharmaceutically active compound, wherein the device is capable of releasing said pharmaceutically active compound such as angiogenesis promoting factors, inhibit...
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WO/2021/110623A1 |
The present invention relates to a medical tubing comprising a thermoplastic polyurethane.
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WO/2021/107141A1 |
The present invention addresses the problem of providing a zwitterion compound that has excellent protein adsoprtion–suppressing action. A zwitterion compound that is a polymer that includes units represented by formula (1) (in which R...
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WO/2021/102136A1 |
The present subject matter relates to a polyurethane composition comprising a polyurethane with at least one free acid group salted with a biguanide free base.
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