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WO/2008/079610A2 |
The present invention relates to compounds of formula (I); Pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic diseases or conditions are also provided.
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WO/2008/071059A1 |
A slurry catalyst that can be directly used in slurry bed to synthesize methanol and dimethylether and the preparation thereof. The catalyst is prepared by a full liquid phase method from solution to slurry, without the traditional slurr...
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WO/2008/071582A1 |
The present invention relates to a nonionic emulsifier for spontaneous emulsification, containing a chemical compound having the general structure tallow alcohol - n PO - m EO, the average number of hydrocarbon atoms of the tallow alcoho...
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WO/2008/073350A2 |
The invention relates to radiolabeled compounds and their use in methods of imaging amyloid deposits, as well as to methods of their manufacture. The invention also relates to compounds for inhibiting the aggregation of amyloid proteins ...
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WO/2008/068310A1 |
This invention relates to campholenic derivatives of general formula (I) wherein Rl, R2, R3, R4 and R5 represent, each independently, a hydrogen atom or a linear or branched C1-C5 alkyl or C2-C5 alkenyl group, Y represents a CN, a C(O)R6...
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WO/2008/069980A1 |
The present invention relates to processes for making dibutyl ethers using aqueous ethanol optionally obtained from a fermentation broth. The dibutyl ethers so formed find use as additives for fuels, including transportation fuels.
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WO/2008/070606A1 |
A hydrofluoroether compound comprises two terminal, independently fluoroalkyl or perfluoroalkyl groups and an intervening oxytetrafluoroethylidene moiety (-OCF(CF3)-) bonded through its central carbon atom to an alkoxy- or fluoroalkoxy-s...
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WO/2008/066580A1 |
The present invention relates to a process for making dibutyl ethers using dry 2-butanol derived from fermentation broth. The dibutyl ethers so produced are useful in transportation fuels.
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WO/2008/066579A1 |
The present invention relates to a catalytic process for making dibutyl ethers using a reactant comprising 2-butanol and water. The dibutyl ethers so produced are useful in transportation fuels.
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WO/2008/064991A1 |
The present invention relates to a process for preparing 3-alkoxy-propan-1-ols of the general formula (I) by catalytic hydrogenation of esters of the general formula (II), where the radicals R1 and R2 and R3, R4 and R5 can be, independen...
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WO/2008/059709A1 |
A process for production of alkylene oxide adducts which comprises subjecting an alkylene oxide adduct containing reaction product obtained by reacting an aliphatic alcohol having a hydrocarbon group of 6 to 22 carbon atoms with an alkyl...
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WO/2008/059771A1 |
A process for producing a fullerene derivative, comprising the organic group addition step (A) of reacting at least a Grignard reagent and a polar substance with fullerene or a fullerene derivative so as to attain addition of an organic ...
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WO/2008/055941A1 |
Process for preparing a compound of the formula (I) in which R1 and R2 are each independently H, C1-C8-alkyl, halogen, polyhalo-C1-C8-alkoxy, polyhalo-C1-C8-alkyl, C1-C8-alkoxy, C1-C8-alkoxy-C1-C8-alkyl, or C1-C8-alkoxy-C1-C8-alkoxy, whe...
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WO/2008/055849A1 |
The present invention relates to a process for the preparation of 2,5-bis(2,2,2-trifluoroethoxy)toluene (II). The compound 2,5-bis(2,2,2-trifluoroethoxy)toluene is useful as intermediate for pharmaceutical industry, especially useful as ...
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WO/2008/056768A1 |
A process for the production of metal catalyst carrying carbon/ethylenediamine composites, characterized by reacting carbon carrying a metal catalyst with ethylenediamine in water or a liquid mixture of water with a water-soluble organic...
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WO/2008/053108A1 |
The invention relates to a process for synthesizing polyacetals by reaction of at least one aldehyde and/or one ketone with a low-molecular-weight polyacetal, using a simulated mobile-bed reactor of which the columns are packed with a be...
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WO/2008/049328A1 |
Disclosed is a process for producing light olefins from methanol and/or dimethyl ether, which comprises the following steps: (a) introducing raw materials containing methanol and/or dimethyl ether into the bottom of a fluidized bed react...
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WO/2008/046239A1 |
Described are 2,2,3-trimethylcyclopent-3-enecarbaldehyde derivatives of formula (I) wherein R1 - R7 have the same meaning as given in the specification. The invention furthermore relates to a method of their production and to fragrance c...
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WO/2008/037040A2 |
The present invention refers to a process for the preparation of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether (sevoflurane) which includes a step that consists of reacting hexafluoroisopropanol with a formaldehyde equival...
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WO/2008/038801A1 |
A method of synthesizing a diol or a polydiol by reductively coupling carbonyl compounds in a solvent with the use of 12CaO.7Al2O3 having 1019 cm-3 or more but not more than 2.3x1021 cm-3 electrons per cage as a reducing agent. A method ...
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WO/2008/038578A1 |
Disclosed are an optically active quaternary ammonium salt having axial asymmetry and a method for producing an α-amino acid and a derivative thereof by using the quaternary ammonium salt. The optically active quaternary ammonium salt h...
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WO/2008/037039A2 |
The present invention refers to a process for the preparation of chloromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether (sevochlorane), which consists of reacting hexafluoroisopropanol with: a formaldehyde equivalent selected betwe...
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WO/2008/035358A2 |
This invention relates to a new process for preparation of enantiomerically pure dapoxetine or an acid addition salt thereof i.e. S(+)-N,N-dimethyl-2-[2-(naphthalenyl oxy)ethyl]benzenemethanamine hydrochoride, a potent serotonin re-uptak...
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WO/2008/033836A2 |
The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
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WO/2008/031333A1 |
The invention disclosed a total synthesis process of novel ethoxy combretastatins and their prodrugs. Combretastatins are chemically modified by ethoxy substituted on the 4'-position of their B aryl ring and are converted to be their sol...
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WO/2008/033336A2 |
A process for the preparation of an allyloxytrifluoropropene derivative of the formula CF3CH=CR1(OCH2CR=CH2) wherein R1 is hydrogen, fluoro, or an allyloxy group represented by the formula - OCH2CR=CH2 wherein R is hydrogen or methyl inc...
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WO2005095311A9 |
Conventional compounds exhibiting a negative dielectric constant anisotropy although exhibiting a negative dielectric constant anisotropy of relatively large numeric value are not appropriate in the balance of properties as a liquid crys...
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WO/2008/028586A1 |
The invention relates to a method for producing alkylene oxide addition products by reaction of compounds having a nucleophilic center with alkylene oxides in a reactor having a large inner surface. The invention is characterized in that...
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WO/2008/028587A1 |
The invention relates to a method for producing alkylene oxide addition products. The method according to the invention is characterized by (a) contacting ethylene and/or propylene with an oxidizing agent in a first structured reactor ("...
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WO/2008/028845A1 |
The instant invention relates to a composition comprising a) an organic material which is susceptible to oxidative, thermal or light-induced degra- dation, and b) at least one compound of the formula (I) wherein the general symbols are a...
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WO/2008/030771A1 |
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
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WO/2008/025254A1 |
Disclosed is a process for starting up fluidized reaction means, which is used for producing lower olefins from methanol or/and dimethyl ether. Said process includes after heating the catalyst bed of circulating fluidized catalytic react...
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WO/2008/026140A2 |
The invention relates to a malodor counteractancy or counteracting (MOC) method that resorts to the use of specific malodor counteracting (MOC) mixtures of fragrance ingredients. More particularly, the invention relates to new MOC compos...
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WO/2008/027604A2 |
RF-compositions including surfactants, foam stabilizers, monomers, polymers, urethanes, intermediates, metal complexes, phosphate esters as well as telomerization methods are provided.
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WO/2008/027780A1 |
This invention provides a process of preparing reaction-derived decahalodiphenyl oxide of high purity. The process comprises cofeeding separate feeds of (a) diphenyl oxide and/or partially brominated diphenyl oxide and (b) bromine chlori...
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WO/2008/023438A1 |
A process for producing 2-fluoro-6-halophenols as intermediates; a process for producing 2-alkoxy-3-fluorophenols, and further 1,2-dialkoxy-3-fluorobenzenes, from the 2-fluoro-6-halophenols; a second process for producing 1,2-dialkoxy-3-...
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WO/2008/023780A1 |
It is intended to provide a method of rapid methylation of an aromatic compound or an alkenyl compound, which is capable of obtaining an aromatic compound or an alkenyl compound labeled with a methyl group or a fluoromethyl group under a...
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WO/2008/019596A1 |
Disclosed is a process for co-producing ethylene and dimethyl ether comprising the steps of (i) providing raw materials containing ethanol and methanol in a weight ratio of methanol to ethanol of from 1:10 to 10:1; (ii) feeding said raw ...
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WO/2008/019306A2 |
The present invention relates to a chemical genus of 3-(triaryl)-2-aminopropanol derivative inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention of inflammatory diseases and disorders.
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WO/2008/019111A2 |
Telomer compositions are provided that can include at least one taxogen unit and a telogon unit, the taxogen unit being one or more of TFP, PFP, VDF, TFMA, PMVE, VF1 TFE, CTFE, BrTFE, HFP, dichlorodif luoroethylene, chlorodifluoroethylen...
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WO/2008/016428A2 |
The present invention relates to a process for making butenes using dry isobutanol derived from fermentation broth. The butenes so produced may be converted to isoalkanes, alkyl-substituted aromatics, isooctanes, isooctanols, and octyl e...
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WO/2008/015241A1 |
The present invention is related to a family of phenyl-prenyl-ether derivatives of formula (I), and to their use in the treatment of cognitive, neurodegenerative or neuronal diseases or disorders, such as Alzheimer's disease or 5 Parkins...
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WO/2008/012321A1 |
A subject-matter of the present invention is a novel process for the synthesis of (E)- stilbene derivatives targeted at obtaining in particular resveratrol and piceatannol.
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WO/2008/012108A2 |
The invention relates to a process for the preparation of polyhydroxylated stilbenes starting from a compound of the formula (I) formula (VI) or formula (IX).
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WO/2008/009409A1 |
Process for the production of alkyl ethers by the etherification of isobutene, contained in C4-C5 hydrocarbon streams, with linear alcohol, in the presence of acid catalysts, comprising the following essential steps: a) feeding the isobu...
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WO/2008/006276A1 |
A type of novel compounds having the symmetric structure of formula I, which can inhibit the congregation and fibrosis of β-amyloid protein, their pharmaceutically accepted salts, and preparation methods thereof. The pharmaceutical comp...
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WO/2008/004788A1 |
The present invention relates tonovel cyclic derivatives having potent inhibiting effect on melanin formation and skin hyper-pigmentation activity with no adverse response to skin, therefore, they can be used as the therapeutics for trea...
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WO/2008/004544A1 |
A process for the production of an alcohol compound represented by the formula (III), comprising reacting a phenol represented by the formula (I) with a haloalcohol represented by the formula (II) in a biphase system composed of a water-...
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WO/2008/003737A1 |
The invention relates to a novel method for producing 3,3'-dihydroxyisorenieratine of formula (I), and to novel intermediate products obtained according to said method.
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WO/2008/004466A1 |
An α-fluoromethoxycarboxylic ester represented by the general formula (1): (CF3)2C(OCH2F)COOR (wherein R is an optionally substituted hydrocarbon group), which is a novel compound; a process for producing 1,1,1,3,3,3-hexafluoroisopropyl...
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