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WO/2001/045681A2 |
Substituted naphthalenediones in accord with structural diagram (I): compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compound...
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WO/2001/042243A2 |
Disclosed are compounds which inhibit or modulate the activity of protein kinases and pharmaceutical compositions containing such compounds. The disclosed compound contain two or more ligand moieties covalently linked together by one or ...
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WO/2001/026485A1 |
The invention relates to the food industry, medicine and agriculture and makes it possible to transform vitamins belonging to a group which is soluble in lipids into an easily available aqueous form or to create complex preparations of l...
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WO/2001/025179A1 |
The invention provides a process for preparing deoxytetracyclic compounds of formula (I) useful in the synthesis of anthracyclines by the rearrangement of thiono ester derivatives followed by reduction, as well as intermediates useful th...
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WO/2001/023329A1 |
The invention relates to a method for brominating organic compounds and to bromination microreactors for carrying out said method.
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WO/2000/066528A2 |
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
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WO/2000/051958A1 |
A process for forming 4-ketocyclopentene and substituted 4-ketocyclopentene compounds starting from the corresponding 1-carbohydroxarbyloxy-2-keto-4-hydroxy-5-cyclopentene by reduction followed by decarboxylation. The ketone may thereaft...
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WO/2000/023377A1 |
The invention concerns a novel method for preparing MEL-type titanium silicalite, the resulting product and its different uses in the field of catalysis. The inventive method for preparing MEL-type titanium silicalite is characterised in...
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WO/2000/008495A2 |
The present invention provides a compound selected from the group consisting of (I), (II), and (III), wherein R?1¿ and R?4¿ are the same or different and are each H, C¿1?-C¿3? alkyl, phosphate, or C¿1?-C¿3? alkyl carboxylate; R?2¿...
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WO/2000/000428A1 |
A method for synthesizing hydrogen peroxide comprises the steps of: synthesizing an analog of anthraquinone that is miscible or soluble in carbon dioxide; reacting the analog of anthraquinone with hydrogen in carbon dioxide to produce a ...
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WO/1999/052819A1 |
The invention relates to the anthraquinone cycle for producing hydrogen peroxide using at least two differently substituted 2-alkylanthraquinones and/or their tetrahydro derivatives. According to the inventive method, the working solutio...
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WO/1999/043316A1 |
Coenzyme Q is obtained by subjecting a mixture from soybeans, particularly a deodorizer distillate, and the like to molecular distillation, supercritical extraction or column chromatography.
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WO/1999/006347A1 |
Use of 1,3,4,6-tetrahydroxy-helianthrone and substituted derivative thereof as photoactivators for the photodynamic therapy of tumors. There are also provided novel substituted derivatives of 1,2,4,6-tetrahydroxy-helianthrone.
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WO/1998/047837A1 |
The invention relates to the use of compounds of formula (I): R?1��a?Re�b?O�c?. L�d? as catalysts for the oxidation of aromatic compounds rich in electrons and of derivatives of such compounds, whereby the catalysts are used in...
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WO/1998/039337A1 |
Process for synthesising pure enantiomer anthracycline. Compounds of formula (I) can be produced by using compounds of formulas (II) and (III).
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WO/1998/033757A1 |
The invention concerns a novel method for preparing substituted anthraquinone represented by the general formula (I) in which R represents a hydrogen atom or a linear or branched alkyl group of 1 to 5 carbon atoms, a chloromethyl group, ...
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WO/1998/018746A1 |
The invention concerns a novel method of preparing trimethyl hydroquinone (THMQ) by oxidising trimethylphenol (TMP). It concerns more particularly a method for oxidising trimethylphenol by a catalytic system consisting of heteropolyacids.
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WO/1998/001410A1 |
It is described a process for the preparation of optically active anthracyclinones via an optically active oxirane by performing the Sharpless reaction under particular and specific conditions.
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WO/1997/031936A2 |
A novel synthetic method, novel compounds formed using the synthetic method, and uses for the compounds so made are described. The synthetic method results in the formation of o-naphthoquinone derivatives. These compounds find use as pot...
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WO/1997/021684A1 |
The therapeutical use of tricyclic derivatives and pharmaceutically acceptable salts thereof having general formula (I), for treating diseases related to venous function deficiency and/or inflammatory oedema, is disclosed. In general for...
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WO/1997/021709A1 |
The therapeutical use of tetracyclic derivatives and pharmaceutically acceptable salts thereof having general formula (I), for treating diseases related to venous function deficiency and/or inflammatory oedema, is disclosed. In general f...
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WO/1997/016404A1 |
A novel method for preparing substituted anthraquinones of general formula (I), wherein R is hydrogen atom or a straight or branched C1-5 alkyl group, a chloromethyl group, a -COCl group, a -COOR' group or a -CH2OR' group where R' is a h...
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WO/1997/003940A1 |
The present invention relates to a novel 6-substituted-5,8-dioxy-1,4-naphthoquinone derivative having formula (I), which is useful as an anticancer agent. In said formula, R1 represents alkyl; R2 represents hydrogen, alkyl or acyl; and R...
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WO/1997/002271A1 |
This invention relates to certain naphthoquinone derivatives of general formula (1) or a salt thereof, in which m, n, R, R1, R2, R3, R4, R5, R6, R7, R8 are as defined in the description; processes for their preparation; compositions cont...
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WO/1996/033015A1 |
A process is provided for preparing a catalyst system containing a catalyst support and an associated catalyst used to catalytically dehydrogenate a hydroquinone. In accordance with the process, the catalyst support is pretreated by sele...
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WO/1996/029297A1 |
A method of making a mesoporous silicate molecular sieve having a framework wall thickness of at least about 17 angstroms, comprising preparing solutions of neutral amine or diamine templating agents, neutral metal silicate precursors an...
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WO/1996/028410A1 |
A method comprising breaking down a complex of 2-(4'-ethylbenzoyl)benzoic acid, nHF and mBF3 to almost completely eliminate HF and BF3. The remaining solid is cyclised in concentrated sulphuric acid or oleum into non-pure 2-ethyl-anthraq...
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WO/1996/022269A1 |
A process for producing quinones by the liquid-phase reaction of an aromatic diol compound with a peroxide in the presence of a catalyst of component (I) containing one or more element selected from the group consisting of platinum, pall...
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WO/1996/021355A1 |
Pesticidal compounds having general formula (I) or a salt thereof is provided, in which n represents an integer from 0 to 4; m represents an integer 0 or 1; each R independently represents a halogen atom or a nitro, cyano, hydroxyl, alky...
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WO/1996/021354A1 |
Pesticidal as a pesticide against whitefly, Lepidoptera and certain fungi is provided of compound of general formula (I) or a salt thereof is provided, in which n represents an integer from 0 to 4; m represents an integer 0 or 1; each R ...
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WO/1996/010005A1 |
A process for catalytically dehydrogenating an anthrahydroquinone to form anthraquinone and a hydrogen product. A catalyst which is a metal, a metal compound, or a metal or metal compound dispersed on a support or is a liquid is selected...
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WO/1996/004895A1 |
The present invention provides the new use in the treatment of amyloidosis with the anthracyclinone of formula (A) wherein R1, R2, R3, R4 and R5, are appropriate substituents. Some compounds of formula (A) are novel. Processes for their ...
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WO/1996/004230A1 |
Terpene-quinone with antitumor activity defined from a cyclocondensation reaction of Diels-Alder, used to obtain families or series of said compounds having a new structure and presenting a cytotoxic activity to cellular cultures P-388, ...
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WO/1996/004292A1 |
8-fluoro-anthracyclines of formula (I) having cis-stereochemistry between the groups 8-F and 9-OH, are described, such compounds present anti-tumor activity. Their preparation and pharmaceutical compositions containing them are also desc...
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WO/1995/032176A1 |
The invention relates to certain naphthoquinone derivatives, some of which are novel, of general formula (I) in which R represents a hydrogen atom or a hydroxyl or an ethanoyloxy group; methods for their preparation; compositions contain...
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WO/1995/018082A1 |
An ozonide reducing agent to be used in the ozonolysis of organic compounds, which has a wide application area and is industrially safe, inexpensive, and easy to aftertreat. The agent is a compound bearing a sulfur atom and, bonded there...
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WO/1995/003267A1 |
The present invention relates to 1,2-benzoquinones; methods of preparation of 1,2-benzoquinones that include preparation of 4,5-substituted- 1,2-benzoquinones in a one-pot reaction; and methods of treatment and pharmaceutical composition...
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WO/1995/002572A1 |
The present invention relates to a process for preparing 5,8-dihydronaphthoquinone derivatives represented by general formula (I) in which R1 represents alkyl or alkenyl, R2 represents hydrogen, alkyl or a group -C(O)R wherein R represen...
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WO/1994/017055A1 |
The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present inventive methods. The antiviral naphthoquinone...
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WO/1994/012431A1 |
A process for converting hydrogen sulfide which is contained in a gaseous feed stream to elemental sulfur and hydrogen. The process comprises contacting said gaseous feed stream with a polar organic solvent having an anthraquinone, and o...
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WO/1993/018208A1 |
An integrated process for oxidizing aromatic and alkyl aromatic compounds to form carbonyl containing reaction products comprising the reaction of quadravalent cerium with a reactant stream containing an aromatic or alkyl aromatic compou...
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WO/1993/015607A1 |
Ion pairs of hypericin and its analogues and derivatives are prepared by acidifying hypericin to its free acid form and reacting with a predetermined quantity of an organic or inorganic base at a pH below about 11.5. The compounds are us...
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WO/1993/002710A2 |
The present invention provides the use of a persistent aryloxy or arylthio free radicals, other than perhalo radicals, for the manufacture of a contrast medium for use in magnetic resonance imaging. Also provided are magnetic resonance i...
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WO/1993/002711A1 |
The present invention provides the use of a persistent $g(p)-system free radical for the manufacture of a contrast medium for use in magnetic resonance imaging, wherein the electron delocalising $g(p)-system of said radical comprises at ...
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WO/1992/006944A1 |
A process for the preparation of a naphtho-1,4-quinone, which process comprises oxidising a naphthalene by the action of an aqueous solution of a cerium (IV) salt and an acid, characterised in that the oxidation is conducted in the prese...
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WO/1991/010634A1 |
Nitrogen-containing aromatic heterocyclic ligand-metal complexes and their use for the activation of hydrogen peroxide and dioxygen are disclosed. Processes whereby activated hydrogen peroxide or dioxygen are used to transform various or...
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WO/1991/001288A1 |
The invention concerns a method for the preparation of chloranil by chlorinating 1 mole of hydroquinone with 4 to about 8 moles of chlorine gas in about 15 to about 37 % by wt. hydrochloric acid at temperatures between about 10 �C and ...
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WO/1990/009974A1 |
4-Substituted anthracyclinones of general formula (I), wherein R represents a hydrogen atom or a COOR1 group in which R1 may be a hydrogen atom or an optionally substituted C1-C10 alkyl group, which are intermediates in the preparation o...
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WO/1990/004601A1 |
4-substituted anthracyclinones of formula (I), wherein R represents a straight or branched alkyl, alkenyl or alkynyl group of up to 16 carbon atoms optionally substituted by (a) an aryl group which is unsubstituted or substituted by an i...
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WO/1989/002886A2 |
The new 2-neopentylanthraquinone compound, which is produced by Friedel-Crafts acylation of neopenthylbenzene with phthalic anhydride followed by cyclization of the 2-(4-neopentylbenzoyl) benzoic acid obtained in the presence of strong a...
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