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WO/1994/004480A1 |
Provided is a facile three step process for preparing 2-phenylterephthalic acid starting with p-xylene, followed by alkylation, dehydrogenation, and oxidation of the methyl groups corresponding to the original p-xylene. The product, 2-ph...
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WO/1994/001388A1 |
Novel difunctionalized cyclobutabenzene monomers of general formula (I), wherein Z can be hydrogens or a cyclobutane ring; and X and Y are carboxyl, amino, alcohol, isocyanate, acid halide, or bis-acyl fluoride groups. Methods of making ...
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WO/1994/000413A1 |
Disclosed is a method for preparing an aromatic carboxylic acid comprising oxidizing in the liquid phase an aromatic feed compound containing at least one alkyl or acyl group with a molecular oxygen-containing gas, in a solvent comprisin...
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WO/1993/025223A1 |
The invention provides a method of screening a substance for the ability to affect the formation of a retinoid X receptor homodimer comprising combining the substance and a solution containing retinoid X receptors and determining the pre...
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WO/1993/025530A2 |
A process and pharmaceutical compositions for treating several diseases and conditions which are normally treatable with retinoid-like compounds are disclosed where the compounds used for the treatment are substantially non-teratogenic a...
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WO/1993/024440A1 |
A process for the production of purified terephthalic acid comprises subjecting an aqueous solution of crude terephthalic acid to hydrogenation to reduce impurities therein, crystallising the resulting solution to produce a slurry of pur...
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WO/1993/024441A1 |
A process for the production of purified terephthalic acid (PTA) from crude terephthalic acid (CTA) comprising mixing the CTA with an aqueous medium to form an aqueous CTA mixture, heating the mixture to dissolve substantially all of the...
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WO/1993/024442A1 |
A medicine containing a benzoic acid derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, and any of novel benzoic acid derivatives represented by general formulae (II), (III) and (IV), all include...
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WO/1993/023359A1 |
In plant for the production and processing of an aromatic carboxylic acid such as terephthalic acid, at least some of the plant components (especially those exposed to an acidic reaction medium at elevated temperatures and pressures in e...
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WO/1993/021146A1 |
Compounds, compositions, and method for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to member...
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WO/1993/015067A1 |
Benzopyran and other benzo-fused leukotriene B4 antagonists have formula (I) wherein R1 is a phenyl or substituted phenyl group, and A, n, R2 and R3 are as defined herein.
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WO/1993/012065A1 |
A process for preparing purified 2,6-naphthalenedicarboxylic acid comprises hydrolyzing a dialkyl-2,6-naphthalenedicarboxylate with water at a reaction temperature of at least about 450 °F under liquid phase condition, the amount of wat...
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WO/1993/009777A1 |
The present invention relates to novel tocotrienols and tocotrienol-like compounds displaying biological activity. The tocotrienols and tocotrienol-like compounds of this invention may be conveniently obtained from biological sources or ...
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WO/1993/009077A2 |
A process for the preparation of 2-chloro-4,5-difluorobenzoic acid and 2,4,5-trifluorobenzoic acid as well as synthetic intermediates useful in and prepared according thereto, comprising reacting a nitrobenzene having formula (II), where...
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WO/1993/008156A1 |
Salts that contain AA-PBZ monomer ions and BB-PBZ monomer ions is precipitated from an aqueous solution by contacting soluble salts of the monomers in an aqueous solution. The monomer salt is polymerized by ordinary techniques to form po...
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WO/1993/008151A1 |
Provided is a continuous process for producing 2,6-naphthalenedicarboxylic acid by the liquid phase oxidation of 2,6-dimethylnaphthalene comprising continuously adding to a reaction zone the oxidation reaction components comprising 2,6-d...
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WO/1993/003113A1 |
Disclosed are liquid-crystal compounds of formula (I), in which R is H, an unsubstituted alkyl or alkenyl group with 1 to 15 C-atoms or an alkyl or alkenyl group with 1 to 15 C-atoms substituted with one CN or CF¿3? group or with at lea...
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WO/1992/021644A1 |
This invention relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, -CH=CH-, or -CH=N-; wherein R1 is -CO2R2 or tetrazole; wherein R2 is hydrogen, alkyl of 1 to 6 carbons or a p...
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WO/1992/021643A1 |
Novel azulenic retinoid compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents. The compositions of the present invention will also find use in tre...
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WO/1992/021645A1 |
A process for preparing purified dimethyl-2,6-naphthalenedicarboxylate by the esterification of 2,6-naphthalenedicarboxylic acid is disclosed and which process provides for the efficient removal of the mono methyl ester of 2,6-naphthalen...
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WO/1992/019583A1 |
Aromatic bicyclic compounds of formula (I) where R1 is specifically -H, -CH3, -CH2OH, -OH, -CHO, -CONH2, -COOH, -COOalkyl, -SH, -S-alkyl, etc...; R2 is H; R3 is H, aryl, aralkyl or lower alkyl optionally substituted by a hydroxyl, a lowe...
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WO/1992/018453A1 |
A process is disclosed for counter-current positive displacement of an aliphatic carboxylic acid of 1 to 5 carbon atoms from a filter cake of an aromatic polycarboxylic acid containing the aliphatic carboxylic acid wherein mother liquor ...
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WO/1992/018454A1 |
A process is disclosed for preparation of purified terephthalic acid containing 200 ppmw or less of p-toluic acid. A filter cake of purified terephthalic acid is prepared by filtering, under a differential pressure of about or greater th...
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WO/1992/015545A1 |
The invention concerns basic calcium aluminium hydroxide dicarboxylates of the following formula: Ca�x?Al�2?(OH)�2(x+3-y)?A�y? . m H�2?O, wherein x is a number between 2 and 12; (2x+5)/2 > y > 0; m is a number between 0 and 12;...
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WO/1992/013928A1 |
Described are liquid-crystal compounds of formula (I), in which R may be H, an alkyl or alkylene group with 1 to 15 C-atoms which is unsubstituted or which is substituted with a single CN or CF�3? group or with at least one halogen ato...
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WO/1992/011120A1 |
A method of melt granulation for powdery material is disclosed wherein the powdery material is discharged onto the upper surface of a heated rotary spreader (10) for migration under centrifugal force to the periphery of the spreader acco...
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WO/1992/009551A1 |
Disclosed is an improved process for the continuous production ofaromatic carboxylic acids such as terephthalic acid by the liquid-phase oxidation of an alkyl aromatic compound using an oxygen-containing gas. Operation of the process is ...
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WO/1992/005139A1 |
A process for the preparation of 3,3',4,4'-biphenyltetracarboxylic acid salt by the dehalodimerization of a 4-halophthalic acid salt. The process uses hydroxylamine or one of its salts as the reducing agent in an alkaline solution prefer...
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WO/1991/017208A1 |
Metal soaps of polycarboxylic acids or polycarboxylic acid partial esters of the general formula (I), A-O-CO-X-CO-O-B in which: A and B together is a metal ion from the group formed by Mg?2+�, Ca?2+� and Zn?2+?? or A is alkyl or alke...
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WO/1991/016308A1 |
3,4,6-trifluorophthalic acid is prepared in high yield by reaction of a 3,4,6-trichloro-N-substituted phthalimide with potassium fluoride at temperatures in the range of 200� to 270 �C in the absence of a catalyst to form the corresp...
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WO/1991/011421A1 |
The invention describes basic calcium aluminium hydroxyde dicarboxylates of the general formula: Ca�x?Al�2?(OH)�2(x+2)?A. m H�2?O in which x = 2 - 8; m = 0 -12; and A is an aliphatic, aromatic or heteroaromatic dicarboxylic acid ...
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WO/1991/010684A1 |
Biologically active oxidized variants of granulocyte-macrophage colony stimulating factor (GM-CSF) are provided in which one or more methionine residues are oxidized. Methods are also provided for making and characterizing such variants.
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WO/1991/009004A1 |
Ester bonds are hydrolyzed, such as in the conversion of polyesters to their monomeric components, by being contacted with a mixture of (a) an alcohol, such as methanol, or glycol, (b) a polar aprotic solvent such as N-methyl-pyrrolidone...
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WO/1991/003161A1 |
A method is provided for controlling the growth of weeds that comprises applying to the weeds a chemical such as a herbicide and a bacterial plant pathogen. Actions of the chemical facilitates opportunistic infection of the weeds by the ...
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WO/1991/002713A1 |
An alkyl o-toluate is subjected to oxidative coupling in an atmosphere containing molecular oxygen in the presence of a catalyst containing a mixture of a palladium salt with 1,10-phenanthroline or alpha,alpha'-bipyridine, a chelate comp...
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WO/1991/001307A2 |
Formula (I), wherein R is a polyvalent aliphatic, substituted aliphatic, aromatic, or substituted aromatic radical and n is an integer having a value of 2 or greater. Polyfunctional N-cyanoimides and their precursors and derivatives are ...
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WO/1990/015046A1 |
A method for removing impurities from an oxidative terephthalic acid synthesis mother liquor containing acetic acid, water, corrosion metals, a metal catalyst and organic impuritites, comprising the steps of (a) removing from the mother ...
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WO/1990/015042A2 |
The present invention is directed to a compound and a process for preparing a compound having at least one perfluorovinyl group and at least one functional group, the compound suitable for reacting with and/or forming polymers. The compo...
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WO/1990/014258A1 |
In a braking installation with a main brake cylinder (1), two braking circuits and an anti-lock and drive slip control device, these controls are operated by a feed pump (32). This feed pump (32) is linked to a store (19) which is connec...
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WO/1990/012780A1 |
The present invention comprises coumponds of formulas (I), (II), (III), wherein X is Cl or Br. These compounds are useful as intermediaries for the production of 2,4,5-trifluorobenzoic acid and 2,4,5-trifluorobenzoyl fluoride.
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WO/1990/009367A1 |
The invention concerns a process for manufacturing a DMT intermediate product and its subsequent processing to high-purity DMT and high-purity and ultrapure terephthalic acid. The DMT intermediate product is manufactured by joint oxidati...
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WO/1990/006669A2 |
A process is disclosed for the co-production of aliphatic monocarboxylic acids and polycarboxylic aromatic acids in high selectivity, conversion and yield. The aliphatic monocarboxylic acid can serve as a component of the solvent for the...
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WO/1990/002725A1 |
The invention relates to a process for producing a 2-oxo-3-aromatic carboxylic acid derivative, which comprises reacting an aromatic pyruvic acid derivative with an electrophilic compound in a protic solvent in the presence of a base. Th...
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WO/1989/011323A1 |
The invention relates to a process for efficiently recovering crystals from slurry for a long time by feeding a slurry to a rotary vacuum filter, filtering with suction while rotating a cylindrical filtering member, washing and again fil...
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WO/1989/009357A1 |
A dry seal for a rotatable shaft (36) is disclosed. The seal includes an axially monolithic elastomeric sealing element (11) having a shaft side (12) and a casing side(14). The shaft side is provided with a plurality of radially inwardly...
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WO/1989/008629A1 |
1,4-disubstituted 2,3-difluorobenzenes of formula (I) are suitable as intermediate products in the synthesis of liquid crystal compounds.
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WO/1989/008634A1 |
A process for the production of aromatic carboxylic acids which comprises carbonylating substituted iodoaromatic compounds in the presence of carbon monoxide, a catalytic amount of a transition metal catalyst, and a Bronsted base in a mi...
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WO/1989/006649A2 |
Novel naphthyridine-, and quinolinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermed...
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WO/1989/003374A1 |
2-Acetonaphthones are prepared by heating a ketal or enol ethers of acetyl-substituted benzalacetone at a temperature effective to cyclize the compound and form said 2-acetonaphthones.
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WO/1989/002427A1 |
A process for preparing a 3,4-dihydro 2-naphthanoic acid or an ester thereof comprises heating an alpha-vinyl cinnamic acid or a (C1-C12)alkyl, (C6-C12)aryl, (C6-C12)aralkyl or (C6-C12)alkylaryl ester thereof at a temperature effective t...
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