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WO/2024/086920A1 |
Elevated bile acids in patients with Fontan circulation have an inverse relationship with age, frailty, skeletal muscle mass and body composition, exercise capacity and hemodynamic parameters. While not wishing to be bound to a particula...
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WO/2024/091043A1 |
The present invention relates to a renal proximal tubule organoid, a kidney cancer organoid, a thyroid organoid or a thyroid cancer organoid, a preparation method therefor, and a drug evaluation method using same.
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WO/2024/087251A1 |
A cysteine-residue-specific chemical probe, which has similar reaction capacity and a higher reaction speed in comparison with existing IA chemical probes, and has certain differences in the types of labelled proteins because of a very s...
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WO/2024/089183A1 |
A device and system for collecting aerosol particles contained in an aerosol sample and preparing the sample for analysis. The aerosol can be breath of a human or animal or an environmental sample. In at least some embodiments, the prese...
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WO/2024/091123A1 |
The invention relates to means and methods for analysis of target analytes using nanopore-based sensors, more in particular to methods, nanopore systems and devices for single-molecule profiling of polymers, e.g. polypeptide or polysacch...
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WO/2024/090670A1 |
The present invention relates to a water supply control platform service system and a water supply control platform method. The water supply control platform service system according to an embodiment of the present invention may comprise...
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WO/2024/091186A1 |
The current invention relates to a method of quantitatively determining the concentration of active myrosinase in a sample, the method comprising the steps of (a) adding a portion of the sample comprising active myrosinase to a first ana...
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WO/2024/090634A1 |
The present disclosure relates to a composition comprising a K-opioid receptor agonist for preventing, ameliorating, or treating diseases related to skin whitening or pigmentation.
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WO/2024/090707A1 |
The present invention relates to a device for separating waste resin and other mixtures from a waste resin mixture generated by a nuclear power plant, desorbing radionuclides from the separated waste resin, and recovering and processing ...
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WO/2024/026360A3 |
An improved assay to measure immunogenicity of vaccines while overcoming some of the limitations of current biomarkers of immunogenicity is necessary. Disclosed herein is an assay for measuring inhibition of binding between SARS-CoV-2 Sp...
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WO/2024/088066A1 |
A use of a reagent for detecting a biomarker comprising a Parkinson's disease-related protein deglycase (DJ-1) in the preparation of a sarcopenia diagnosis reagent.
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WO/2024/090399A1 |
The purpose of the present invention is to provide a highly sensitive method for detecting a biomarker. This purpose can be achieved by the method for detecting a test substance in a specimen according to the present invention, which i...
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WO/2024/089270A2 |
The present invention relates to novel pore monomers, pores formed from the pore monomers and their uses in analyte detection and characterisation.
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WO/2024/092055A1 |
Disclosed herein are methods for analzying quantitative expression values of biomarkers of a biomarker panel for determining multiple sclerosis disease activity (e.g., multiple sclerosis disease progression) in a human subject. Further d...
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WO/2024/087370A1 |
The present invention relates to the technical field of molecular biology, and provides a preparation method for a eukaryotic expression-based deoxynivalenol full-length antibody and a use of a eukaryotic expression-based deoxynivalenol ...
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WO/2024/059515A3 |
Natural antibodies are an integral part of innate humoral immunity yet their development and polyreactive nature are still enigmatic. Here it is shown that characteristic monoclonal natural antibodies recognize common chemical moieties o...
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WO/2024/090998A1 |
The present invention relates to a YaxAB nanopore, a system comprising the nanopore and applications thereof. The YaxAB nanopore of the present invention has a funnel-shaped three-dimensional structure so that a change in current blockin...
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WO/2024/088424A1 |
Provided in the present disclosure is an antibody specifically binding to cytotoxic T lymphocyte-associated antigen-4 (CTLA4), particularly a heavy-chain antibody, and more particularly a single-domain antibody. Also disclosed is the the...
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WO/2024/087336A1 |
Disclosed in the present invention are an all-genetically encoded NMN protein probe based on resonance energy transfer, and a use thereof, and particularly, an all-genetically encoded NMN protein probe, which is formed by connecting a re...
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WO/2024/040225A9 |
The present invention relates to the field of nephrology. More specifically, the present invention provides compositions and methods useful for the diagnosis and treatment of acute kidney injury. In a specific embodiment, a method for id...
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WO/2024/090647A1 |
The present invention relates to a device and a method capable of measuring turbidity of water used in home appliances, the device comprising: a fluid storage part comprising a reflector; a first light source that emits light to the flui...
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WO/2024/090927A1 |
The present invention relates to a novel anti-CDCP1 antibody or an antibody fragment thereof. In addition, the present invention relates to: a pharmaceutical composition comprising an anti-CDCP1 antibody or an antibody fragment thereof f...
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WO/2024/087668A1 |
A second near-infrared region (NIR-II) surface-enhanced resonance Raman probe based on safe irradiation dose. The probe has a core-shell structure sequentially comprising a gold nano petal-shaped inner core, an NIR-II resonance Raman rep...
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WO/2024/089180A1 |
The present invention relates to a method to determine the recovery rate of sample extracellular vesicles. The present invention further relates to a kit comprising a control extracellular vesicle. The present invention also relates to m...
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WO/2024/090062A1 |
This antigen discovery method comprises a data acquisition step for acquiring measurement data, a data calculation step, and an antigen selection step. In the data calculation step, antigen data is calculated on the basis of the measurem...
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WO/2024/089614A1 |
A soil properties in-ground probe 1 having a tubular body 101, containing a head 106, in the side of which is an inspection hole 107 protected by glass, the head 106 containing elements of a system for carrying out a measurement of soil ...
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WO/2024/091264A1 |
Chimeric recombinant proteins for the detection of infection by Borreliella and/or diagnosis of Lyme disease are provided. Methods and devices for conducting immunoassays with the chimeric recombinant proteins are also provided.
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WO/2024/059402A3 |
Electrochemical sensor modules for blood gas analyzers are disclosed that can detect the presence of a blood micro clot or deposit on a pH sensor. The electrochemical sensor modules include an integrated sensor chip containing a pH senso...
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WO/2024/091515A1 |
A method for quantifying a cellulosic component in a sample includes preparing a first suspension by mixing an amount of sample with first aqueous acid at a concentration of 40 wt-% or greater; incubating the first suspension in a first ...
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WO/2024/091053A1 |
The present invention relates to a method for predicting the response to immunotherapeutic agents, comprising a step of measuring, in cancer cells or cancer tissue, the expression level of a dexamethasone-induced ras-related protein 1 (D...
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WO/2024/089297A1 |
Disclosed are methods to obtain enhanced variants of fluorescent and bioluminescent proteins based on ratiometric measurement of luminescence. Disclosed are furthermore engineered variants of a yellow fluorescent protein (YFP) derived fr...
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WO/2023/023678A8 |
A mask-based diagnostic apparatus for detecting a biomarker contained in exhaled breath of a test subject. An exhaled breath condensate (EBC) collector converts breath vapor from the lungs and airways into a fluid biosample. The EBC coll...
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WO/2024/092175A1 |
An example method includes receiving data that includes a set of spectral metrics from interactions of electromagnetic radiation with a sample. A first trained model and a second trained model is applied to at least one of the set of spe...
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WO/2024/091447A1 |
Methods of assaying a breath sample from a subject for the presence of one or more toxins or toxin associated compounds are provided. In some embodiments, the one or more toxins or toxin associated compounds includes trichloroethylene (T...
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WO/2024/088629A1 |
The present invention relates to a station (1) for measuring airborne molecular contamination, comprising: - at least one gas analyser (3) configured to measure a concentration of at least one contaminant, - a plurality of air inlets (5)...
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WO/2024/086891A1 |
The present invention relates generally to the identification and/or treatment of cancer and in particular cancers in which gastrin releasing peptide receptor (GRPR) is expressed. In particular embodiments, the present invention relates ...
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WO/2024/064112A3 |
Paramagnetic beads capture a biological target molecule for cryo-electron microscope imaging. Two spacer modules extend from a periphery of the paramagnetic beads comprising a first spacer module and a second spacer module. The first spa...
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WO/2024/087515A1 |
Provided are an anti-CD16A antibody and an application thereof. The antibody comprises heavy chain variable region CDR1, CDR2 and CDR3 sequences as shown in SEQ ID NOs: 1, 2 and 3 respectively, or amino acid sequences at least 95% identi...
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WO/2024/090863A1 |
The present specification provides a method for predicting the prognosis of endometrial cancer and a kit using same, the method comprising the steps of: detecting whether MSH2 or MSH6 is deficient in a biological sample isolated from an ...
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WO/2023/220759A3 |
Systems and methods for oxidizing phenolic cannabinoids with fuel cells are described. The oxidation processes for phenolic cannabinoids and/or Δ9-THC can be detected and the concentration of phenolic cannabinoids and/or Δ9-THC can be ...
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WO/2024/088374A1 |
The present invention provides a method for detecting an analyte in a sample and an immunoassay test strip. A label reagent and a capture reagent are involved. The label reagent comprises a first reagent marked by an analysis marker, the...
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WO/2024/087429A1 |
Use of an antibody for detecting a protein biomarker group in the preparation of a kit for diagnosing Alzheimer's disease (AD), mild cognitive impairment (MCI) and other types of senile dementia. The protein biomarker group comprises a p...
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WO/2024/091456A1 |
A method for intra-operative assessment of a tissue specimen mammogram to predict tumor margin status includes receiving, during breast-conserving surgery, a mammogram of a resected breast tissue specimen. The method further includes pro...
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WO/2023/244680A3 |
Disclosed are peptides that differentially bind to analytes, and methods for obtaining the peptides. Disclosed are methods for determining binding of peptides to analytes by detecting nucleic acids that are associated with the peptides. ...
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WO/2024/090229A1 |
Provided is a method for more easily ensuring the accuracy when analyzing the carbon concentration distribution in accordance with the position in a steel material to be subjected to a carburization treatment. Specifically, this method i...
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WO/2024/089007A1 |
The invention relates to a method for predicting the response to an anti-cancer treatment of patients suffering from cancer, said method being based on the detection of biomarkers. The invention also relates to methods of treatment and m...
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WO/2024/088971A1 |
A method and apparatus for automated patch clamp analysis on a plurality of biological cells clamped in respective patch-clamp wells. At least one of the cells is placed in voltage-clamp mode by applying a respective, defined voltage the...
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WO/2024/087867A1 |
The present invention belongs to the technical field of tectonic fissures in oil exploration. Provided are a characterization method for the in-situ openability of a deep tectonic fissure, and a storage medium. The method comprises: sele...
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WO/2024/090864A1 |
Provided in the present specification are a method for diagnosing endometrial cancer using a nectin-4 expression rate, and a kit using same, the method comprising the steps of: measuring a nectin-4 expression rate in a biological sample ...
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WO/2024/090678A1 |
According to a livestock group sample sampling method and apparatus for livestock regular forecasting, and a livestock regular forecasting system using same, which are proposed in the present invention, by collecting a standard sample an...
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