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WO/2023/041714A1 |
An apparatus (1) and a method for recording spectrally resolved images of a sample (2) are described, wherein a radiation source (3) and optical means (7) comprising single-mode fibers for guiding excitation radiation emitted by the radi...
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WO/2023/043590A1 |
A microscope assembly includes an objective lens and an infinite conjugate tube lens. The effective focal length of the objective lens is not greater than 80mm. The numerical aperture of the microscope is 0.14 or more. The microscope exh...
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WO/2022/028694A9 |
The invention relates to a method for automatically ascertaining an illumination brightness (Pk) to be adjusted of at least two light sources (120k) in order to excite at least one respective fluorophore (130j) in a sample (110) to be im...
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WO/2023/041494A1 |
The invention relates to a method, a microscope (1) and a computer program for localizing and/or imaging light-emitting molecules (M) in a sample (S) contained in a sample reservoir (6) comprising illuminating the sample (S) by a light s...
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WO/2023/036946A1 |
The invention relates to an optical microscope (100) and a microscopy method. According to the invention, the microscope comprises an imaging module (200) comprising an optical beam splitter (40), a first optical system (41, 42, 43), a f...
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WO/2023/037587A1 |
Provided is an angle adjusting member for an optical element, the angle adjusting member being provided with two actuators and a center bar having a tip end portion that is operable through 360°. Furthermore, in order to provide a micro...
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WO/2023/039120A1 |
Generation and use of a focus quality metric that is intensity independent is described. In one example, the focus quality metric is generated by acquiring an image, such as an image of a patterned surface of a flow cell, and processing ...
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WO/2023/035543A1 |
A three-dimensional super-resolution light sheet microscopic imaging method and a microscopic imaging system (1000). The microscopic imaging method comprises: generating excitation light for a biological sample (2000) in a manner of ligh...
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WO/2023/031622A1 |
A system and method for generating sample data for analysis provide an image capture unit configured to capture a stack of images in image layers through a thickness of a sample, each image layer comprising pixel data in two orthogonal p...
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WO/2023/030518A1 |
The present application provides a robot-based cell operation task processing method and apparatus, a device, and a medium. The method comprises: sending an assistance request for a cell operation task to a task assistance terminal (step...
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WO/2023/032398A1 |
This invention addresses the problem of providing a sealing apparatus that makes it possible to: enhance the operability, workability, and safety of initial cover film positioning compared to the prior art; prevent cover film and the app...
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WO/2023/033198A1 |
An embodiment provides a fluorescence lifetime measuring apparatus comprising: a light generator for generating excitation light to be irradiated on a sample; a collector including a first photo-detector for receiving fluorescent photons...
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WO/2023/032352A1 |
Provided is a Raman-infrared spectroscopic analysis multifunction machine comprising an infrared spectroscopic analysis light source and a Raman spectroscopic analysis light source, a plate for fixing a sample, a stage for arranging the ...
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WO/2023/034076A1 |
Resolution of images used in processes such as sequencing by synthesis may be increased by structuring sites that would emit signals in the images to have different elevations. Differences in focus caused by these differences in elevatio...
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WO/2023/034780A1 |
In some embodiments, a system includes a light source configured to emit a first light beam having a first wavelength and a second light beam having a second wavelength. The system further includes an array mask having a set of apertures...
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WO/2023/034532A1 |
A defect detection and imaging system is presented for performing microscopy and/or spectroscopy on a device under test. The defect detection system comprises a controller for toggling the state of a light source, which may allow for fas...
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WO/2023/032394A1 |
The objective of the present invention is to provide a mounting device with which erroneous introduction of a mounting medium is prevented when a mounting medium bottle is being replaced, and with which a coverslip, the mounting medium, ...
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WO/2023/026398A1 |
The spot light generation device pertaining to the present invention comprises an optical modulator having a modulation surface configured so as to be capable of amplitude modulation of incident laser light, and a condensing element for ...
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WO/2023/027610A1 |
The invention is used for classifying blood cells. Proposed is a method, carried out using a claimed device, according to which reference values are set. Next, a camera of a trinocular microscope is activated, a slide is placed on the st...
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WO/2023/027095A1 |
A manipulation system 10 comprises: a manipulator 16 for manipulating a sample 40; a manipulator drive mechanism 26 for moving the manipulator 16; an imaging device 24 for capturing an image of the sample 40 through an objective lens 20;...
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WO/2023/028025A1 |
A method for providing an embedded application associated with identifying microorganisms, foreign matters, and contaminants from water sources, which comprises: transporting dredged material and watery slush from the water sources to co...
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WO/2023/025842A1 |
The present invention relates to an optical slide (10) intended to receive a biological sample for the purposes of total internal reflection microscopy. Such an optical slide comprises a glass base substrate (11) and a stack (12) of thin...
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WO/2023/019400A1 |
A microscopic imaging apparatus and an illumination chip (8) thereof, an imaging method, an electronic device (30), and a medium. The illumination chip (8) comprises: an illumination array structure, which comprises a substrate (81) and ...
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WO/2023/021867A1 |
Provided is a scanning probe microscope in which an objective lens used for radiation of exciting light and collection of Raman scattered light can be disposed closer to a specimen and to a probe. The scanning probe microscope is provide...
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WO/2023/021289A1 |
An apparatus (2) for volumetric imaging is provided. The apparatus (2) comprises an illumination assembly (8) arranged to direct light to illuminate a plurality of planes (22) in a sample region (4) sequentially at an illumination rate, ...
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WO/2023/020902A1 |
The invention relates to a device for observing a biological probe. The device comprises an optical microscope, a beam splitting device and a plurality of cameras. The optical microscope comprises a support structure for supporting the b...
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WO/2023/023552A1 |
Methods and systems are provided for a microscope assembly. In one example, the microscope assembly include an objective arranged at a top of a plate and aligned with a first side of the plate and a tube lens positioned below the objecti...
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WO/2023/022647A1 |
A method for measuring polarization and anisotropy of fluorophores comprises activating (S2) reversibly switchable fluorophores in a sample. The activating comprises applying (S20) of a first activation light pulse of a wavelength suitab...
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WO/2023/023556A1 |
A multichannel tunable lens system may include a review channel with a fluidic focusing device, which can adjust the focus of the channel rapidly to mitigate environmental vibrations. The review channel may generate high resolution image...
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WO/2023/017181A1 |
A microscope (1) for imaging one or more samples (70) is disclosed. The microscope (1) comprises a sample holder (30) comprising a receptacle (40) for holding the one or more samples (70), at least one illumination objective lens (10) fo...
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WO/2023/015798A1 |
A multi-functional two-photon microscopic imaging system. A first excitation light source (1), a first photoelectric modulator (2), a first beam expanding apparatus (3), a reflecting mirror (4) and a first scanning apparatus (5) constitu...
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WO/2023/017083A1 |
The invention relates to a medical imaging device, in particular a stereo endoscope or stereo exoscope, comprising: a light source having a light spectrum; an optical system, which has a first optical path, a first image sensor having a ...
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WO/2023/017418A1 |
A method for super-resolution photoacoustic microscopy of an object. The method includes optically exciting the object according to a plurality of excitation patterns utilizing a digital micromirror device (DMD), receiving a plurality of...
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WO/2023/013325A1 |
Provided is a Raman microspectrometer that makes it possible to achieve size and cost reduction through light disperser structure simplification and is capable of sustained highly accurate sample analysis. A Raman microspectrometer 1 com...
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WO/2023/011905A1 |
Described herein is an optical element, and a metrology tool or system employing the optical element for measurements of structures on a substrate. The optical element includes an optical element includes a first portion configured to re...
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WO/2023/010718A1 |
An elliptical hemispherical curved surface large-field-of-view high-throughput two-photon microscope, comprising: a near-infrared femtosecond pulse laser group (1), a beam splitting and delay module group (2), a scanning unit group (3), ...
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WO/2023/012241A1 |
In some embodiments, a method provides a live view mode without scanning a micro optical element array in which successive image(s) are generated, and optionally displayed, that comprise image pixels that represent sample light received ...
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WO/2023/006915A1 |
The invention relates to a lighting system 1, intended in particular to be installed in a microscope or a microscopic imaging device, comprising a plurality of light sources 2 arranged in plane regions defining a solid space intersecting...
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WO/2023/005942A1 |
A laser scanning imaging method and system, a storage medium, and a computer program. The laser scanning imaging method comprises: determining parameter information related to an effective area, the effective area comprising an imaging a...
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WO/2023/006176A1 |
For determining a molecule position of a singularized fluorophore molecule, a light beam including fluorescence excitation light and fluorescence influencing light is shaped and focused such as to form a light intensity distribution havi...
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WO/2023/007827A1 |
A sample observation device 1 comprises: an irradiation optical system 3 that irradiates a sample S with planar light L2; a scanning unit 4 that has a rotating shaft 12 for rotating the sample S at a predetermined angular speed with resp...
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WO/2023/007828A1 |
A sample observation device 1 comprises a radiation optical system 3 that radiates planar light L2A, L2B of different wavelengths along respective cross-sections that are at different positions on a sample S, a scanning unit 4 that scans...
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WO/2023/010048A1 |
A computer-implemented method of reviewing digital pathology data may include receiving a digital pathology image into a digital storage device, the digital pathology image being associated with a patient, providing for display the digit...
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WO/2023/006366A1 |
The invention relates to a contactless visualization system (1) for a surgical microscope (2) for eye surgery. The contactless visualization system (1) has an ophthalmoscopic magnifying glass (3) which can be positioned in front of a pat...
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WO/2023/006345A1 |
A confocal microscopy apparatus 100 for imaging a sample 2 under investigation by chromatic confocal microscopy comprises an illumination source device 10 being arranged for creating illumination light 1 having an illumination spectrum c...
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WO/2023/006365A1 |
The invention relates to a contactless visualization system (1) for a surgical microscope (2) for eye surgery. The contactless visualization system (1) has an ophthalmoscopic magnifying glass (3) which can be positioned in front of a pat...
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WO/2023/001932A1 |
The invention relates to a method for acquiring a two-dimensional image of a biological sample via scanning microscopy, the sample being located in a reference surface defined by a plurality of pixels. The method comprises the following ...
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WO/2023/002679A1 |
In the present invention, the estimation of a focal position based on an image is prepared in a short amount of time. A focal position estimation system 30 is a system that estimates a focal position when focusing on an estimation targ...
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WO/2023/001931A1 |
The invention relates to a method for acquiring a three-dimensional image of a biological sample by scanning microscopy. The sample is located in a reference volume (V) defined by a plurality of voxels. The method comprises the following...
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WO/2023/002788A1 |
Provided is an objective lens (300) which is used in a sample analysis device (100) for detecting light in a plurality of wavelength bands from particles (P) flowing through a flow channel (C), and is provided in proximity to the flow ch...
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