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Title:
【発明の名称】抗ガン剤としてのDNA結合インドール誘導体、そのプロドラッグ、および免疫結合体
Document Type and Number:
Japanese Patent JP2000511893
Kind Code:
A
Abstract:
The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomeric constituents are derived from monocyclic or bicyclic heterocyclic aromatic residues.

Inventors:
Fan beak, julius, geraldas, theodorus
Light, Susan Sea.
Lalique, Gems W.
Application Number:
JP54289897A
Publication Date:
September 12, 2000
Filing Date:
May 22, 1997
Export Citation:
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Assignee:
Pavel, Eugene
International Classes:
C12P21/08; A61K31/00; A61K31/40; A61K31/403; A61K31/404; A61K31/407; A61K31/415; A61K31/4164; A61K31/4188; A61K31/545; A61K31/546; A61K31/70; A61K31/7028; A61K31/7042; A61K31/7052; A61K31/7056; A61P35/00; C07D209/60; C07D403/06; C07D403/14; C07D405/14; C07D487/04; C07D495/04; C07D501/00; C07D501/22; C07D501/34; C07H15/04; C07H15/24; C07K16/30; (IPC1-7): C07D209/60; A61K31/404; A61K31/407; A61K31/4188; A61K31/546; A61K31/7056; A61P35/00; C07D403/14; C07D405/14; C07D487/04; C07D495/04; C07D501/34; C07H15/04
Attorney, Agent or Firm:
Shusaku Yamamoto