Title:
【発明の名称】置換アミノアルカンホスホン酸
Document Type and Number:
Japanese Patent JP2001502681
Kind Code:
A
Abstract:
PCT No. PCT/EP97/05843 Sec. 371 Date Apr. 23, 1999 Sec. 102(e) Date Apr. 23, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/17672 PCT Pub. Date Apr. 30, 1998Compounds of the formula I in which R1 is hydroxyl or an aliphatic, araliphatic or aromatic radical, X is a divalent aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic, heteroarylaliphatic or aromatic radical, R2 is hydrogen or an aliphatic or araliphatic radical, alk is lower alkylidene and R3, R4 and R5 independently of one another are hydrogen, lower alkyl, halogen, trifluoromethyl, cyano or nitro, and their salts can be used for the treatment of pathological conditions which respond to blockage of excitatory amino acid receptors, and for the production of pharmaceutical preparations.
Inventors:
Aklan, Pierre
Hans, Algaia
Eberson, Eve
Offner, Zilbio
Fernstra, Seam Jacob
Hans, Algaia
Eberson, Eve
Offner, Zilbio
Fernstra, Seam Jacob
Application Number:
JP51897098A
Publication Date:
February 27, 2001
Filing Date:
October 22, 1997
Export Citation:
Assignee:
Novartis Actien Gezel Shaft
International Classes:
A61P9/00; A61P25/00; A61P25/08; A61P43/00; C07F9/6509; A61K31/675; (IPC1-7): C07F9/6509; A61K31/675; A61P9/00; A61P25/00; A61P43/00
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)