【発明の名称】アンチトロンビンIIIの精製方法

Title:

【発明の名称】アンチトロンビンIIIの精製方法

Document Type and Number:

Japanese Patent JP2001517679

Kind Code:

A

Abstract:

A method of purifying antithrombin III (AT III) from a starting material containing an AT III/heparin complex or an AT III/heparinoid complex is disclosed. First, the method comprises adsorbing the AT III/heparin complex or the AT III/heparinoid complex on an anion exchanger material. Second, the method involves separating the AT III from the adsorbed AT III/heparin complex or an AT III/heparinoid complex by elution with a buffer having a pH ranging from 8.5 to 10.5 and a conductivity between 10 and 60 mS.

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Inventors:

Yendra Linnau
Ernst Hetzl
Her Peter Matthiessen
Jillvia Nepple
Wolfgang Schoenhofer
Hans-Peter Schwarz

Application Number:

JP2000512865A

Publication Date:

October 09, 2001

Filing Date:

September 17, 1998

Export Citation:

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Assignee:

Baxter Actien Gezel Shaft

International Classes:

C07K14/81; A61K38/00; (IPC1-7): C07K14/81

Attorney, Agent or Firm:

Aoyama Ryo (1 person outside)

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