Title:
【発明の名称】中枢神経系疾患の予防及び治療のための医薬組成物
Document Type and Number:
Japanese Patent JP2001520628
Kind Code:
A
Abstract:
Patients susceptible to or suffering from central nervous system disorders (e.g., Tourette's syndrome, attention deficit disorder or schizophrenia) are treated by administering an effective amount of an aryl substituted aliphatic compound, an aryl substituted olefinic amine compound or an aryl substituted acetylenic compound. Exemplary compounds are (E)-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-4-[3-(5-methoxypyridin)yl]-3-butene-1-amine, (E)-N-methyl-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-N-methyl-4-[3-(5-methoxypyridin)yl]-3-butene-1-amine, (Z)-metanicotine, (E)-metanicotine, N-methyl-(3-pyridinyl)-butane-1-amine, N-methyl-4-(3-pyridinyl)-3-butyne-1-amine and (E)-N-methyl-4-[3-(6-methylpyridin)yl]-3-butene-1-amine.
Inventors:
Benkeriff, Meroane
Lippiero, Patrick Michael
Caldwell, William Scott
Dal, Gary Morris
Lippiero, Patrick Michael
Caldwell, William Scott
Dal, Gary Morris
Application Number:
JP52117196A
Publication Date:
October 30, 2001
Filing Date:
December 28, 1995
Export Citation:
Assignee:
RJ Reynolds Tobacco Company
International Classes:
A61K31/44; A61K31/4406; A61K31/465; A61K31/505; A61P25/00; A61P25/16; A61P25/18; A61P25/28; C07D213/65; C07D239/26; (IPC1-7): A61K31/44; A61K31/465; A61K31/505; A61P25/00; A61P25/16; A61P25/18; A61P25/28
Attorney, Agent or Firm:
Nao Okuyama (3 others)