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Title:
【発明の名称】抗炎症剤としての置換ピリジン化合物
Document Type and Number:
Japanese Patent JP2001522834
Kind Code:
A
Abstract:
Selected novel substituted pyridine compounds are effective for prophylaxis and treatment of diseases, such as TNF- alpha , IL-1 beta , IL-6 and/or IL-8 mediated diseases, and other maladies, such as pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving inflammation, pain, diabetes, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Inventors:
Mantro, Nathan Bee
Syuractor, Stephen Tay
Ji-yo Ji, Ji Young Ai
Application Number:
JP2000520418A
Publication Date:
November 20, 2001
Filing Date:
November 04, 1998
Export Citation:
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Assignee:
Amjien Incorporated
International Classes:
A61K31/44; A61K31/4418; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/496; A61P1/04; A61P3/10; A61P3/14; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P19/08; A61P19/10; A61P21/06; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/06; A61P37/08; C07D213/73; C07D213/75; C07D213/82; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D471/04; (IPC1-7): C07D213/75; A61K31/44; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/496; A61P1/04; A61P3/10; A61P3/14; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P19/08; A61P19/10; A61P21/06; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/06; A61P37/08; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D471/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)