【発明の名称】環状アミン誘導体、およびその薬剤としての使用法

Japanese Patent JP2001523661

A

A compound represented by general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. Since these compounds inhibit the action of chemokines such as MIP-1 alpha and/or MCP-1 on target cells, they may be useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.

Shioda Tatsuki
Kenichiro Kataoka
Minoru Imai
Takaharu Tsutsumi
Masaki Sudo
Ryo Togawa
Moriya Takuya
Naohiko Haneda
Yumiko Muroka
Takenouchi Sumi
Furuya Minoru
Noriaki Endo
Christine M. Turby
Wilna Molly
Steven El. Tague

JP2000521070A

November 27, 2001

November 17, 1998

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Teijin Limited
DuPont Pharmaceuticals Research Laboratories

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Maeda Junhiro

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