Title:
【発明の名称】プロアントシアニジンポリマー止瀉組成物の腸溶製剤
Document Type and Number:
Japanese Patent JP2001524938
Kind Code:
A
Abstract:
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. Methods for use of the formulations as well as methods for use of the proanthocyanidin polymer composition in combination with an effective amount of a compound effective either to inhibit secretion of stomach acid or to neutralize stomach acid are disclosed.
Inventors:
Lozone, Edward, Jay.
Karndwara, Athur, Es.
Sabouuni, akrum
Karndwara, Athur, Es.
Sabouuni, akrum
Application Number:
JP51863298A
Publication Date:
December 04, 2001
Filing Date:
October 14, 1997
Export Citation:
Assignee:
Sherman Pharmaceuticals, Incorporated
International Classes:
C07D311/62; A61K9/10; A61K9/28; A61K9/32; A61K9/50; A61K9/54; A61K9/58; A61K31/352; A61K31/353; A61K31/765; A61K36/18; A61K47/32; A61P1/12; A61P31/04; (IPC1-7): A61K31/352; A61K9/10; A61K9/32; A61K9/54; A61K9/58; A61K35/78; A61K47/32; A61P1/12; A61P31/04; C07D311/62
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)