Title:
【発明の名称】6-O-アルキルエリスロマイシンCの化学合成
Document Type and Number:
Japanese Patent JP2001525332
Kind Code:
A
Abstract:
A process of preparing a 6-O-alkyl derivative of erythromycin C is provided. The process includes the steps of protecting the 2',4"- and 9-oxime hydroxyls with acetyl and ketal protecting groups, alkylating the 6-hydroxyl, removing the protecting groups and deoximating. Intermediates used in the process are also provided.
Inventors:
Montgomery, Stephen H
Ives, Michael Day
Liu, Chi-Hoa
Ives, Michael Day
Liu, Chi-Hoa
Application Number:
JP2000523224A
Publication Date:
December 11, 2001
Filing Date:
November 17, 1998
Export Citation:
Assignee:
ABBOTT LABORATORIES
International Classes:
A61K31/7042; A61K31/7048; A61P31/04; C07H17/08; (IPC1-7): C07H17/08
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)