Title:
【発明の名称】細胞結合活性を有するコラーゲン様ポリマー
Document Type and Number:
Japanese Patent JP2001527451
Kind Code:
A
Abstract:
The invention is essentially directed to a biocompatible material comprising a bulk material which has covalently bound to a surface or surfaces thereof one or more biopolymer compounds, said biopolymer compounds comprising at least one peptoid residue. The biopolymer compounds are most preferably polymer compounds comprising the sequence of the formula (I): -(Gly-Pro-Nleu)(Y)-, wherein (y) denotes >/=9. Also disclosed is a method of binding biopolymer compounds to a bulk material, which biopolymer compounds comprise at least one peptoid residue, as well as primary amine groups, the method comprising the steps of: (a) providing aldehyde or carboxyl groups on a surface or surfaces of said bulk material; (b) reacting said primary amine groups with aldehyde or carboxyl groups to form covalent bonds.
Inventors:
Steel, John Gerrard
Johnson, Graham
Goodman, Murray
Greeser, Hans Jorg
McLean, Keith Michael
Boomer, Herit Jean
Johnson, Graham
Goodman, Murray
Greeser, Hans Jorg
McLean, Keith Michael
Boomer, Herit Jean
Application Number:
JP54991998A
Publication Date:
December 25, 2001
Filing Date:
May 14, 1998
Export Citation:
Assignee:
Novartis Actien Gezel Shaft
Commonwealth Scientific and Industrial Research Organization
Commonwealth Scientific and Industrial Research Organization
International Classes:
G01N33/544; A61L27/00; A61L27/22; A61L27/34; A61L31/04; A61L31/10; C12N5/07; C12N5/071; (IPC1-7): A61L27/00; C12N5/06; G01N33/544
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)