Title:
【発明の名称】試薬再循環を用いてオリゴマー、特に、ペプトイドを合成するための装置
Document Type and Number:
Japanese Patent JP2001527544
Kind Code:
A
Abstract:
An apparatus is provided for conducting solid phase oligomer synthesis. The apparatus includes a reaction vessel in which a solid phase support is contained. The reaction vessel has a top opening through which gases and solvents can be delivered by way of a series of conduits and valves. The reaction vessel is interconnected through a bottom opening therein and through a series of conduits and valves with a vessel or series of vessels containing a reagent or series of reagents, respectively, required for the synthetic reaction. The reagent vessel serves a both a source of reagent delivered to the reaction vessel and as a repository for unused reagent returned thereto from the reaction vessel. Reagent delivery and mixing is gas-driven using an associated source of an inert gas.
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Inventors:
Zuckerman, Ronald
Trout, quilt
DeRose, Serina
Quay, katy
Owings, matthew
Bursteg, Benjamin
Henry Henry
Trout, quilt
DeRose, Serina
Quay, katy
Owings, matthew
Bursteg, Benjamin
Henry Henry
Application Number:
JP54729898A
Publication Date:
December 25, 2001
Filing Date:
April 28, 1998
Export Citation:
Assignee:
Chiron Corporation
International Classes:
B01J4/00; B01J19/00; C07H21/00; C07K1/04; C40B40/02; C40B50/06; C40B40/10; C40B60/14; (IPC1-7): C07K1/04; B01J4/00
Domestic Patent References:
| JPH08501565A | 1996-02-20 | |||
| JPH06128286A | 1994-05-10 | |||
| JPH0789983A | 1995-04-04 | |||
| JPH0549914A | 1993-03-02 | |||
| JPS60237097A | 1985-11-25 | |||
| JPH05509257A | 1993-12-22 | |||
| JPH06505748A | 1994-06-30 |
Attorney, Agent or Firm:
Shusaku Yamamoto