Title:
【発明の名称】皮膚疾患に対する治療的処置
Document Type and Number:
Japanese Patent JP2002501501
Kind Code:
A
Abstract:
A method for reducing or inhibiting vascular permeability especially the increased vascular permeability associated with VPF/VEGF, and dermal edema exhibited with bullous phemigoid, erythema multiforme, dermatitis herpetiformis, contact dermatitis/delayed hypersensitivity is disclosed, particularly using the beta -isozyme selective PKC inhibitor, (S)-3,4-ÄN,N'-1,1'-((2"-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butan e)-bis-(3,3'-indolyl)Ü-1(H)-pyrrole-2,5-dione and its pharmaceutically acceptable salts.
Inventors:
Jiro Seck Michael Earl.
Strum Lawrence Yi.
Vignati Lewis
Ways Douglas Kay.
Strum Lawrence Yi.
Vignati Lewis
Ways Douglas Kay.
Application Number:
JP54706598A
Publication Date:
January 15, 2002
Filing Date:
April 21, 1998
Export Citation:
Assignee:
ELI LILLY AND COMPANY
International Classes:
A61K31/00; A61K31/407; A61P17/00; A61P43/00; A61K45/00; (IPC1-7): A61K45/00; A61K31/407; A61P17/00; A61P43/00
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)