Title:
【発明の名称】潜在的反応性血液適合性作用物質
Document Type and Number:
Japanese Patent JP2002506688
Kind Code:
A
Abstract:
A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a spacer group linking the latent reactive group to the aliphatic acid in a manner that preserves the desired function of each group. Once bound to the surface, via the latent reactive group, the reagent presents the aliphatic acid to the physiological environment, in vivo, in a manner (e.g., concentration and orientation) sufficient to hold and orient albumin.
Inventors:
Guyer, Patrick E.
Anderson, Aaron Bee.
Amos, Richard A.
Everson, Terrence Pee.
Anderson, Aaron Bee.
Amos, Richard A.
Everson, Terrence Pee.
Application Number:
JP2000536415A
Publication Date:
March 05, 2002
Filing Date:
March 11, 1999
Export Citation:
Assignee:
Thermo Dicks, Incorporated
International Classes:
A61L27/00; A61K47/48; A61L31/04; A61L33/00; (IPC1-7): A61L33/00; A61L27/00
Attorney, Agent or Firm:
Takashi Ishida (4 others)