Title:
【発明の名称】7-ヘキサノイルタキソール(登録商標)及びその調製法
Document Type and Number:
Japanese Patent JP2002511457
Kind Code:
A
Abstract:
An antitumor compound of formula (5) and also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2' and 7 positions of paclitaxel is followed by the hydrolysis of the 2' hexanoate group resulting in 7-hexanoyltaxol.
Inventors:
Marley, Christopher, Kay.
Chen, Kung, Wai.
Shakuya, Sagar, Earl.
Chen, Kung, Wai.
Shakuya, Sagar, Earl.
Application Number:
JP2000543447A
Publication Date:
April 16, 2002
Filing Date:
April 09, 1999
Export Citation:
Assignee:
Hauser, Incorporated
International Classes:
A61K31/337; A61P35/00; A61P35/02; C07D305/14; (IPC1-7): C07D305/14; A61K31/337; A61P35/00; A61P35/02
Attorney, Agent or Firm:
Shinichi Ogawa (2 outside)