Title:
【発明の名称】造影剤
Document Type and Number:
Japanese Patent JP2002511845
Kind Code:
A
Abstract:
The invention provides a method of generating an image of an animate human or non-human animal subject previously administered with a contrast agent involving generating an image of at least a part of said subject to which said contrast agent has distributed, characterised in that said contrast agent is a composition of matter of formula I V - L - R where V is a vector moiety having affinity for an angiogenesis-related endothelial cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterised in that V is a non-peptidic organic group, or V is peptidic and R is a macromolecular or particulate species providing a multiplicity of labels detectable in in vivo imaging.
Inventors:
Clavenes, You
Newestard, Anne
Torres Haug, Helge
Newestard, Anne
Torres Haug, Helge
Application Number:
JP54530798A
Publication Date:
April 16, 2002
Filing Date:
April 24, 1998
Export Citation:
Assignee:
Niyucomed Imaging Axiesel Capet
International Classes:
C12N15/09; A61K47/48; A61K49/00; A61K49/08; A61K49/18; A61K49/22; A61K51/04; A61K51/08; A61K51/12; C07D233/02; C07D239/94; C07D401/12; (IPC1-7): A61K49/00; C07D233/02; C07D239/94; C07D401/12
Domestic Patent References:
| JPH06336484A | 1994-12-06 | |||
| JPH04500823A | 1992-02-13 | |||
| JPH07509460A | 1995-10-19 | |||
| JPH07509459A | 1995-10-19 | |||
| JPH08505763A | 1996-06-25 | |||
| JPH08506594A | 1996-07-16 | |||
| JP2000507930A | 2000-06-27 |
Foreign References:
| WO1995014491A2 | 1995-06-01 | |||
| WO1997033552A1 | 1997-09-18 | |||
| WO1997030035A1 | 1997-08-21 | |||
| WO1997037655A1 | 1997-10-16 |
Attorney, Agent or Firm:
Chika Takagi (1 person outside)