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Title:
【発明の名称】アゲラガラスタチンと命名されたヒトのがん細胞増殖を阻害する化合物の分離と構造の解明。
Document Type and Number:
Japanese Patent JP2002517424
Kind Code:
A
Abstract:
A human cancer cell line bioassay-directed investigation of the Western Pacific marine sponge agelas sp. led to isolation of a trace (7.42x10-6% yield) cancer cell growth inhibitor (lung NCI-H460 GI50 0.77 mug/ml to ovary OVCAR-3 GI50 2.8 mug/ml) designated agelagalastatin. Agelagalastatin is the first example of a natural product containing a digalactofuranosyl unit.

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Inventors:
George Earl Pettit
Jun Ping Fu
Application Number:
JP2000553015A
Publication Date:
June 18, 2002
Filing Date:
June 09, 1999
Export Citation:
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Assignee:
Arizona Board of Regents
International Classes:
A61K31/7028; A61P35/00; C07H15/04; (IPC1-7): C07H15/04; A61K31/7028; A61P35/00
Attorney, Agent or Firm:
Nao Kuwahara



 
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