Title:
【発明の名称】リンチトリプトのカリウム塩の製造法
Document Type and Number:
Japanese Patent JP2002521383
Kind Code:
A
Abstract:
A method for preparing the potassium dihydrate salt of 2-[[4-(2-chlorophenyl)-2-thiazolyl]carbamoyl]indole-1-acetic acid, by reacting 2-[[4-(2-chlorophenyl)-2-thiazolyl]carbamoyl]indole-1-acetic acid or its C1-C4 alkyl esters with potassium carbonate in a two phase solvent system comprising a mixture of water and an organic solvent which is only slightly miscible with water and optionally recrystallising the precipitated intermediate solvate from water and to the potassium dihydrate salt thus obtained.
Inventors:
Radisson, gel
Application Number:
JP2000561189A
Publication Date:
July 16, 2002
Filing Date:
July 15, 1999
Export Citation:
Assignee:
SANOFI-SYNTHELABO
International Classes:
C07D417/12; (IPC1-7): C07D417/12
Attorney, Agent or Firm:
Shintaro Nogawa