Title:
【発明の名称】心臓血管に適用するための組み合わせ
Document Type and Number:
Japanese Patent JP2002533411
Kind Code:
A
Abstract:
The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia and atherosclerosis. Combinations disclosed include an ileal bile acid transport inhibitor combined with a cholesteryl ester transport protein (CETP) inhibitor, a fibric acid derivative, a nicotinic acid derivative, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, a phytosterol, a stanol, an antihypertensive agent, or others. Further combinations include a CETP inhibitor with a fibric acid derivative, a nicotinic acid derivative, a bile acid sequestrant, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, or others.
Inventors:
Keller Bradley Tee.
Reiz David Bee.
Shoe Joseph Earl.
Sikorski James A.
Tremont Samuel Jay.
Rap Rodney W.
Reiz David Bee.
Shoe Joseph Earl.
Sikorski James A.
Tremont Samuel Jay.
Rap Rodney W.
Application Number:
JP2000590676A
Publication Date:
October 08, 2002
Filing Date:
December 17, 1999
Export Citation:
Assignee:
G.D.Searle LRC
International Classes:
A61K31/095; A61K31/365; A61K31/397; A61K31/4178; A61K31/55; A61K31/554; A61K31/575; A61K31/585; A61K31/77; A61K45/00; A61P3/06; A61K45/06; A61P9/00; A61P9/10; A61K; A61P; C07D; (IPC1-7): A61K45/06; A61K31/095; A61K31/365; A61K31/397; A61K31/4178; A61K31/55; A61K31/554; A61K31/575; A61K31/585; A61K31/77; A61K45/00; A61P3/06; A61P9/10
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)
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