Title:
【発明の名称】宿主細胞タンパク質を有する感染性因子を標的化するための方法及び製剤
Document Type and Number:
Japanese Patent JP2002543162
Kind Code:
A
Abstract:
A formulation is disclosed for the treatment of diseases caused by an infectious agent which acquires host membranes protein during its life cycle. The formulation is a targeting pharmaceutical composition. It comprises a ligand capable of binding the host membrane proteins coupled to a lipid-comprising vesicle, which may comprise or not a drug effective in the treatment of the disease. Specific liposomes bearing anti-HLA-DR or anti-CD4 antibodies comprising or not antiviral drugs, namely anti-HIV drugs, are disclosed and claimed. A method of formulation as well as a method of using the formulation in the treatment of a disease are also disclosed.
Inventors:
Michelle Bergeron
André Dusolmo
Michelle J. Trenbrae
André Dusolmo
Michelle J. Trenbrae
Application Number:
JP2000615056A
Publication Date:
December 17, 2002
Filing Date:
May 03, 2000
Export Citation:
Assignee:
Infectio Richelicher Incorporated
International Classes:
A61K9/127; A61K31/43; A61K31/7068; A61K45/00; A61K47/24; A61K47/68; A61K47/69; A61P31/18; (IPC1-7): A61K47/48; A61K9/127; A61K31/43; A61K31/7068; A61K45/00; A61K47/24; A61K47/34; A61P31/18
Attorney, Agent or Firm:
Masatake Shiga (7 outside)