【発明の名称】赤血球および血小板を含む血液製剤の、改良された貯蔵および維持法 - SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI

Title:

【発明の名称】赤血球および血小板を含む血液製剤の、改良された貯蔵および維持法

Document Type and Number:

Japanese Patent JP2003501364

Kind Code:

A

Abstract:

Cell membrane maintenance of red blood cells and platelet concentrates is improved by the addition of 1 mM-10 mM L-carnitine and derivatives. This improvement allows extension of the period of viability of packed red blood cells and platelet concentrations beyond current periods. Additionally, the materials so treated exhibit extended circulation half life upon transfusion to a patient. Improvements in membrane maintenance achieved by this method permit irradiation of sealed containers of blood products so as to substantially sterilize and destroy leukocytes in the same.

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Inventors:

Second Doturi

Application Number:

JP2001501034A

Publication Date:

January 14, 2003

Filing Date:

June 05, 2000

Export Citation:

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Assignee:

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI

International Classes:

A01N1/02; A61K35/14; A61K35/18; A61J3/00; A61L2/00; C12N5/02; C12N7/01; (IPC1-7): A61K35/14; A01N1/02; A61K35/18

Domestic Patent References:

JPH05339218A	1993-12-21
JPS63283643A	1988-11-21

Foreign References:

WO1998046073A1

1998-10-22

Attorney, Agent or Firm:

Aoyama Ryo (2 outside people)

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