Title:
【発明の名称】前立腺癌の治療に有用な複合体
Document Type and Number:
Japanese Patent JP2003512339
Kind Code:
A
Abstract:
The present invention is directed to the improved synthesis of compounds of formula I:which may be useful in the treatment of prostate cancer. Such compounds are synthesized in the presence of a carboxyl activating agent, an additive and a base for the preparation of a PSA conjugate which comprises an anthracycline antibiotic and an oligopeptide.
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Inventors:
Lynch, Yosef Yi
Robins, Michael A
Xi, Yao-Chiyun
Lieberman, David Earl
Robins, Michael A
Xi, Yao-Chiyun
Lieberman, David Earl
Application Number:
JP2001531421A
Publication Date:
April 02, 2003
Filing Date:
October 18, 2000
Export Citation:
Assignee:
Merck End-Campany Inc.
International Classes:
A61K38/00; A61K47/48; A61P35/00; C07K1/10; (IPC1-7): C07K1/10; A61K38/00; A61P35/00
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)