Title:
【発明の名称】ジアリール-エニン類
Document Type and Number:
Japanese Patent JP2003513063
Kind Code:
A
Abstract:
Provided, among other things, is a compound of Formula (I), wherein, Ar1 and Ar2 are independently selected aryl groups, optionally substituted with up to five substituents independently selected from the group consisting of alkyl, alkoxy, cycloalkyl, cycloalkyloxy, heterocycloalkyl, heterocycloalkyloxy, alkanoyl, thioalkyl, aralkyl, aralkyloxy, aryloxyalkyl, aryloxyalkoxy, cycloalkyl-substituted alkyl, cycloalkyloxy-substituted alkyl, cycloalkyl-substituted alkoxy, cycloalkyloxy-substituted alkoxy, heterocycloalkyl-substituted alkyl, heterocycloalkyloxy-substituted alkyl, heterocycloalkyl-substituted alkoxy, heterocycloalkyloxy-substituted alkoxy, thioaryl, aralkylthio, thioarylalkyl, aralkylthioalkyl, halo, NO2, CF3, CN, OH, alkylenedioxy, SO2NRR', NRR', CO2R (where R and R' are independently selected from the group consisting of H and alkyl), and a second aryl group, which may be substituted as above; R1 is selected from the group consisting of H and alkyl; R2 is selected from the group consisting of H, alkyl and benzyl; R3 is selected from the group consisting of CO2R, CONRR', CONH(OH), COSR, SO2NRR', PO(OR)(OR') and tetrazolyl, wherein R and R' are independently selected from the group consisting of H and alkyl; and a salt, solvate or hydrate thereof.
Inventors:
Egret, Ian
Frey, Jennifer
Isaac, metbin
Frey, Jennifer
Isaac, metbin
Application Number:
JP2001534756A
Publication Date:
April 08, 2003
Filing Date:
November 01, 2000
Export Citation:
Assignee:
NPS Allelic Corporation
International Classes:
A61K31/21; A61K31/223; A61K31/36; A61K31/381; A61K31/40; A61K31/47; A61K31/695; A61P25/18; A61P25/28; C07C229/14; C07C229/36; C07C323/32; C07C323/41; C07D207/325; C07D207/335; C07D215/12; C07D307/52; C07D317/58; C07D333/20; C07D207/32; (IPC1-7): C07C229/14; A61K31/223; A61K31/36; A61K31/381; A61K31/40; A61K31/47; A61K31/695; A61P25/18; A61P25/28; C07C323/32; C07D207/335; C07D215/12; C07D307/52; C07D317/58; C07D333/20
Domestic Patent References:
| JP2002519322A | 2002-07-02 | |||
| JP2002505332A | 2002-02-19 | |||
| JP2002505277A | 2002-02-19 | |||
| JP2000501707A | 2000-02-15 | |||
| JP2002519322A | 2002-07-02 | |||
| JP2002505332A | 2002-02-19 | |||
| JP2002505277A | 2002-02-19 | |||
| JP2000501707A | 2000-02-15 |
Attorney, Agent or Firm:
Akitoshi Otawa (1 outside)