Title:
【発明の名称】プレガバリンの不斉合成
Document Type and Number:
Japanese Patent JP2003520841
Kind Code:
A
Abstract:
This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.
Inventors:
Burke, Mark Joseph
Goel, Ohm Prakash
Ho Extra, Marvin Simon
Mitch, Thomas Frederick
Malhan, Thomas Arthur
Rumsden, James Andrew
Goel, Ohm Prakash
Ho Extra, Marvin Simon
Mitch, Thomas Frederick
Malhan, Thomas Arthur
Rumsden, James Andrew
Application Number:
JP2001555033A
Publication Date:
July 08, 2003
Filing Date:
January 11, 2001
Export Citation:
Assignee:
WARNER-LAMBERT COMPANYLLC
International Classes:
C07B53/00; C07B61/00; C07C227/04; C07C227/10; C07C229/08; C07C253/30; C07C255/19; C07C255/23; (IPC1-7): C07C253/30; C07C227/04; C07C229/08; C07C255/19
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)
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